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FMGE 2010 — Pediatrics

Q: In males, first pubertal sign is:

Testicular enlargement. ***Testicular enlargement*** - The first noticeable sign of puberty in males is typically **testicular enlargement**, followed by other changes. - This enlargement is due to the increase in the size of the **seminiferous tubules** and the production of sperm. *Pubic hair development* - While pubic hair development is an important pubertal sign, it usually follows **testicular enlargement**, appearing as the second or third sign. - It is driven by the increase in **adrenal androgens** and **testosterone**. *Hoarseness of voice* - The voice change or **deepening (hoarseness)** usually occurs later in puberty, as the larynx grows and vocal cords lengthen. - This is a secondary sexual characteristic mediated by **testosterone**. *Penis enlargement* - **Penis enlargement** typically begins after testicular enlargement has been established, usually around a Tanner stage 3. - This growth is also directly stimulated by increasing levels of **testosterone**. [Practice more Pediatrics PYQs on OnCourse]

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In males, first pubertal sign is:

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