Pharmacology
1 questionsAll are symptoms of morphine withdrawal except?
NEET-PG 2013 - Pharmacology NEET-PG Practice Questions and MCQs
Question 1311: All are symptoms of morphine withdrawal except?
- A. Yawning
- B. Lacrimation
- C. Mydriasis
- D. Fall in BP (Correct Answer)
Explanation: ***Fall in BP*** - **Hypotension (fall in BP)** is **not** typically a symptom of opioid withdrawal; rather, **hypertension** can occur due to sympathetic overdrive. - Opioid withdrawal symptoms are primarily characterized by **hyperactivity** and increased sympathetic nervous system activity. *Mydriasis* - **Mydriasis (dilated pupils)** is a classic symptom of opioid withdrawal, resulting from reduced parasympathetic tone and increased sympathetic activity. - In contrast, opioid intoxication causes **miosis (pinpoint pupils)**. *Yawning* - **Yawning** is a very common and early symptom of opioid withdrawal, often accompanied by feelings of fatigue and restlessness. - It reflects generalized **autonomic dysregulation** during withdrawal. *Lacrimation* - **Lacrimation (tearing)** is another prominent autonomic symptom of opioid withdrawal. - This, along with rhinorrhea, contributes to the **"flu-like" symptoms** experienced during withdrawal.
Psychiatry
8 questionsWhich of the following is NOT a diagnostic criterion for drug dependence?
Which of the following can cause delirium?
Visual hallucinations are typically seen in all of the following conditions except?
Waxy flexibility is a feature of ?
Which type of delusion is primarily associated with Cotard's syndrome?
Which of the following statements about hallucinations is true?
Who coined the term 'psychiatry'?
Psychoanalysis was started by?
NEET-PG 2013 - Psychiatry NEET-PG Practice Questions and MCQs
Question 1311: Which of the following is NOT a diagnostic criterion for drug dependence?
- A. Taking substance in larger amounts than intended
- B. Tolerance
- C. Withdrawal symptoms
- D. Early completion of tasks (Correct Answer)
Explanation: ***Early completion of tasks*** - This is not a recognized diagnostic criterion for **drug dependence (substance use disorder)** according to standardized diagnostic manuals like the DSM-5. - While it might reflect an individual's productivity or efficiency, it has no direct link to the compulsive drug-seeking and use behaviors characteristic of dependence. *Tolerance* - **Tolerance** is a core criterion, defined as a need for markedly increased amounts of the substance to achieve intoxication or desired effect, or a markedly diminished effect with continued use of the same amount of the substance. - This indicates a physiological adaptation to the presence of the drug. *Withdrawal symptoms* - **Withdrawal symptoms** refer to the characteristic physiological and psychological symptoms that occur when a person stops or reduces their use of a substance after prolonged or heavy use. - The presence of a withdrawal syndrome or taking the substance (or a closely related one) to relieve or avoid withdrawal symptoms is a key diagnostic indicator. *Taking substance in larger amounts than intended* - This criterion reflects the **impaired control** over substance use, where the individual uses the substance more often or in larger quantities than they initially intended. - It demonstrates a loss of conscious regulation over drug intake, which is a hallmark of substance dependence.
Question 1312: Which of the following can cause delirium?
- A. Hypoxia
- B. Barbiturates
- C. Alcohol withdrawal
- D. All of the options (Correct Answer)
Explanation: ***All of the options*** - **Delirium** is an acute, fluctuating disturbance in attention and cognition, often with altered consciousness, and can be caused by a wide range of factors. - **Hypoxia**, **barbiturate** use, and **alcohol withdrawal** are all well-established causes of delirium. *Hypoxia* - **Cerebral hypoxia**, or insufficient oxygen supply to the brain, directly impairs neuronal function, leading to acute confusion and altered mental status characteristic of delirium. - Conditions like severe respiratory failure, heart failure, or anemia can precipitate hypoxia and subsequent delirium. *Barbiturates* - **Barbiturates** are central nervous system depressants that can cause sedation, confusion, and cognitive impairment, especially in overdose or in susceptible individuals. - While they typically induce sedation, paradoxical excitement or severe cognitive dysfunction consistent with delirium can occur. *Alcohol withdrawal* - **Alcohol withdrawal** can lead to a severe form of delirium known as *delirium tremens*, characterized by extreme confusion, hallucinations, tremors, and autonomic instability. - The rapid cessation of chronic alcohol intake disrupts neurochemical balance, leading to hyperexcitability and delirium.
Question 1313: Visual hallucinations are typically seen in all of the following conditions except?
- A. Schizophrenia
- B. Alcohol withdrawal
- C. Delirium
- D. Depression (Correct Answer)
Explanation: **Depression** - While other forms of hallucinations can occur in severe depression with psychotic features (e.g., auditory), **visual hallucinations are rare**. - **Mood-congruent delusions** are more common in psychotic depression than visual hallucinations. *Delirium* - **Visual hallucinations** are a hallmark symptom of delirium, often described as polymorphic and vivid. - They are typically accompanied by **fluctuating consciousness** and cognitive impairment. *Schizophrenia* - Although **auditory hallucinations** are more common, visual hallucinations can occur in schizophrenia, particularly in advanced or severe cases. - These hallucinations are often well-formed, frequent, and can be **persecutory** or **bizarre** in nature. *Alcohol withdrawal* - **Alcohol withdrawal delirium** (delirium tremens) is characterized by prominent **visual hallucinations**, tactile hallucinations, and autonomic instability. - These hallucinations can be terrifying and are due to **CNS hyperexcitability**.
Question 1314: Waxy flexibility is a feature of ?
- A. Catatonia (Correct Answer)
- B. Echolalia
- C. Stereotypy
- D. Mannerisms
Explanation: ***Catatonia*** - **Waxy flexibility** (or catalepsy) is a classic symptom of **catatonia**, where an individual's limbs can be **placed in any position by the examiner and remain in that position for an extended period**, as if molded from wax. - It reflects a severe psychomotor disturbance, often seen in conditions like **schizophrenia** or **mood disorders** with catatonic features. *Echolalia* - **Echolalia** refers to the **involuntary repetition of another person's spoken words**, typically without understanding. - It is a symptom of thought disorder or communication difficulties, not a state of motor rigidity. *Stereotypy* - **Stereotypy** involves **repetitive, seemingly purposeless movements or utterances** (e.g., body rocking, hand flapping). - While repetitive, it does not involve maintaining a fixed posture imposed by another, as seen in waxy flexibility. *Mannerisms* - **Mannerisms** are **habitual, idiosyncratic gestures or behaviors** that may appear odd but are often voluntary and goal-directed (e.g., an exaggerated bow before speaking). - They are distinct from the involuntary, often rigid, posturing characteristic of waxy flexibility.
Question 1315: Which type of delusion is primarily associated with Cotard's syndrome?
- A. Persecutory delusions
- B. Religious delusions
- C. Nihilistic delusions (Correct Answer)
- D. Hypochondriacal delusions
Explanation: ***Nihilistic delusions*** - **Cotard's syndrome** is characterized by beliefs of **non-existence**, such as the patient being dead, not existing, or having lost their organs, which are typical of **nihilistic delusions**. - These delusions can also extend to the belief that the world or parts of it no longer exist. *Persecutory delusions* - These involve the belief that one is being **harassed, tricked, spied upon, or conspired against**, which is not the primary feature of Cotard's syndrome. - While they can co-occur with other psychiatric conditions, **persecutory themes** are distinct from the non-existence themes of Cotard's. *Religious delusions* - These delusions focus on **religious or spiritual themes**, such as believing one is a prophet or has a special relationship with a deity. - They are not a core component of Cotard's syndrome, which centers on themes of **death and non-existence**. *Hypochondriacal delusions* - These involve a preoccupation with the belief that one has a **serious, undiagnosed medical condition**, despite medical reassurance. - While Cotard's syndrome can involve bodily concerns, the belief in **non-existence of organs** or death goes beyond typical hypochondriacal fears of illness.
Question 1316: Which of the following statements about hallucinations is true?
- A. There is misinterpretation of external stimulus
- B. Can be controlled by voluntary effort
- C. Perceived as real but without an external stimulus (Correct Answer)
- D. Always indicates severe mental illness
Explanation: ***Perceived as real but without an external stimulus*** - Hallucinations are defined by the perception of sensory experiences (e.g., seeing, hearing, feeling) that **feel real to the individual** but have **no corresponding external stimulus**. - This fundamental characteristic distinguishes them from other perceptual distortions like illusions. *There is misinterpretation of external stimulus* - This describes an **illusion**, where an actual external stimulus is misinterpreted (e.g., seeing a coat in the dark and believing it's a person). - Hallucinations occur in the **absence of any external stimulus**, making this statement incorrect for defining hallucinations. *Can be controlled by voluntary effort* - Hallucinations, being involuntary sensory experiences, are generally **not amenable to conscious control** or suppression by the individual experiencing them. - The lack of voluntary control is a key feature distinguishing them from imagination or fantasy. *Always indicates severe mental illness* - While often associated with severe mental illnesses like **schizophrenia**, hallucinations can also occur due to various other causes, including **substance intoxication or withdrawal**, neurological conditions (e.g., delirium, Parkinson's disease), or even during periods of extreme fatigue or stress. - Therefore, stating they *always* indicate severe mental illness is inaccurate.
Question 1317: Who coined the term 'psychiatry'?
- A. Moral
- B. Bleuler
- C. Pinel
- D. Johann Reil (Correct Answer)
Explanation: ***Johann Reil*** - The term "**psychiatry**" (Psychiatrie) was coined by the German physician **Johann Christian Reil** in **1808**. - Reil introduced the term in his work to advocate for a more **humane and medical approach** to mental illness, moving away from purely custodial care. *Moral* - While Reil's efforts were part of a broader movement towards **moral treatment** of the mentally ill, "moral" itself is not the specific context in which the term was coined. - **Moral treatment** emphasized humane care, occupational therapy, and a therapeutic environment, contributing to the development of psychiatry but not coining the word. *Bleuler* - **Eugen Bleuler** is known for coining the term "**schizophrenia**" in the early 20th century. - He significantly contributed to the understanding of psychotic disorders but did not coin the broader term "psychiatry." *Pinel* - **Philippe Pinel** was a French physician who was an instrumental figure in the **humanitarian reform** of mental asylum care in the late 18th century. - He is famous for **unshackling patients** at Bicêtre and Salpêtrière asylums, but he did not coin the term "psychiatry."
Question 1318: Psychoanalysis was started by?
- A. Eugen Bleuler
- B. Sigmund Freud (Correct Answer)
- C. Carl Jung
- D. Erik Erikson
Explanation: ***Sigmund Freud*** - **Sigmund Freud** is widely recognized as the founder of **psychoanalysis**. - He developed theories on the **unconscious mind**, **psychosexual development**, and the use of techniques like **free association** and dream analysis. *Eugen Bleuler* - **Eugen Bleuler** was a Swiss psychiatrist who coined the term "**schizophrenia**." - While influential in psychiatry, his work was primarily focused on **descriptive psychopathology**, not the founding of psychoanalysis. *Carl Jung* - **Carl Jung** was a student of Freud who later diverged to develop his own school of thought called **analytical psychology**. - His contributions include concepts like the **collective unconscious**, archetypes, and psychological types. *Erik Erikson* - **Erik Erikson** was a developmental psychologist and psychoanalyst known for his theory of **psychosocial development**. - He expanded on Freud's work by focusing on the influence of social factors and the **lifespan stages** on personality development.
Radiology
1 questionsWhich imaging modality is most effective in differentiating between epidermoid cyst and arachnoid cyst?
NEET-PG 2013 - Radiology NEET-PG Practice Questions and MCQs
Question 1311: Which imaging modality is most effective in differentiating between epidermoid cyst and arachnoid cyst?
- A. Magnetic Resonance Imaging (MRI) (Correct Answer)
- B. Ultrasound (USG)
- C. Computed Tomography (CT) scan
- D. Positron Emission Tomography (PET) scan
Explanation: ***Magnetic Resonance Imaging (MRI)*** - **MRI** is superior for differentiating epidermoid and arachnoid cysts due to its excellent **soft tissue contrast** and ability to detect fluid signal characteristics. - **Diffusion-weighted imaging (DWI)**, a specific MRI sequence, is crucial; **epidermoid cysts** show high signal on DWI (diffusion restriction) due to their keratin content, while **arachnoid cysts** follow CSF signal on all sequences and do not restrict diffusion. *Ultrasound (USG)* - **Ultrasound** has limited utility for intracranial lesions in adults due to the bony skull, which prevents sound wave penetration. - It may be used in infants through the fontanelles but lacks the resolution and specific sequences needed to characterize these cysts. *Computed Tomography (CT) scan* - While a **CT scan** can identify these cysts as hypodense lesions, it lacks the detailed **tissue characterization** and signal patterns provided by MRI. - Both cysts would appear as **hypodense lesions**, making differentiation difficult based on density alone, especially after contrast administration. *Positron Emission Tomography (PET) scan* - A **PET scan** primarily assesses metabolic activity and would not effectively differentiate between benign **non-metabolic cysts** like epidermoid and arachnoid cysts. - It is more commonly used for detecting **malignancies** or assessing brain activity patterns, not for structural differentiation of fluid-filled lesions.