Question 1

Question

A 4-year-old boy with sickle cell disease presents to the emergency department with fever of 39.5°C (103.1°F), lethargy, and tachycardia. His last vaccination was 6 months ago. BP is 85/50 mmHg, HR 160/min, RR 36/min. He appears ill with capillary refill of 4 seconds. Labs show: WBC 2,500/μL with 60% neutrophils, hemoglobin 6.2 g/dL (baseline 7.5 g/dL), platelets 95,000/μL, reticulocyte count 0.2%. Evaluate the prioritization of management interventions for this presentation.

Accepted Answer

Fluid bolus, blood cultures and empiric ceftriaxone plus vancomycin, then address anemia

Answer

Exchange transfusion for acute chest syndrome

Answer

Hydroxyurea initiation and antipyretics with close monitoring

Answer

Immediate packed RBC transfusion as the primary intervention

Answer

Broad-spectrum IV antibiotics after blood culture, then fluid resuscitation

Pediatric emergency management — MCQs

Pediatric emergency management — MCQs

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