Question 1

Question

A 32-year-old pregnant woman at 32 weeks gestation presents with a 2-day history of low-grade fever, headache, and myalgias. She works at a daycare where several children recently had 'slapped cheek' rash. Laboratory studies show hemoglobin 8.5 g/dL (baseline 12 g/dL), reticulocyte count 0.1%, and positive parvovirus B19 IgM. Fetal ultrasound shows hydrops fetalis with ascites, pleural effusions, and severe anemia on cordocentesis. Evaluate the pathophysiologic mechanism and management approach that best addresses both maternal and fetal complications.

Accepted Answer

Vertical transmission causing fetal aplastic crisis; intrauterine transfusion with close monitoring

Answer

Fetal cardiac failure from myocarditis; deliver immediately for neonatal intensive care

Answer

Placental insufficiency from maternal viremia; administer antivirals and corticosteroids

Answer

Maternal immune thrombocytopenia causing fetal bleeding; administer IVIG to mother

Answer

Maternal-fetal ABO incompatibility exacerbated by viral infection; plasmapheresis

Vaccine-preventable diseases — MCQs

Vaccine-preventable diseases — MCQs

On this page

Practice by Chapter

Want unlimited practice?