Urology Practice Questions

Q: A young male presents with a testicular mass on the right side. The AFP is elevated while the HCG is normal. The most appropriate next step is

Orchidectomy. ***Radical Inguinal Orchidectomy*** - In a patient who already presents with a **testicular mass** and **elevated AFP** (suggesting non-seminomatous germ cell tumor), the most appropriate next step is **radical inguinal orchidectomy**. - This procedure is both **diagnostic and therapeutic**, providing tissue for histopathological confirmation while removing the primary tumor. - The standard management sequence is: clinical examination → scrotal USG → tumor markers → **orchidectomy** → staging imaging → further treatment based on histology and stage. - Since the mass is already identified and tumor markers are done, proceeding directly to orchidectomy is appropriate. *USG* - Scrotal **ultrasound** is typically the **first imaging modality** when a testicular mass is suspected or palpated. - However, in this scenario, the mass is already clinically identified and tumor markers (AFP) have been measured, suggesting that initial workup including USG has likely been completed. - USG would have been the appropriate answer if the question asked for the "first investigation" before tumor markers were done. *Biopsy* - Direct **biopsy** of a testicular mass is **contraindicated** due to the high risk of tumor cell spillage along the needle tract, which can alter staging and worsen prognosis. - Testicular cancer is diagnosed via **radical inguinal orchidectomy**, not biopsy. *Wait and Watch* - A **wait and watch** approach is inappropriate and dangerous in the presence of a **testicular mass with elevated AFP**, which strongly suggests malignancy (non-seminomatous germ cell tumor). - Delayed treatment can lead to disease progression, metastasis, and poorer outcomes.

Q: A 45-year-old male presenting with penile cancer extending up to the glans penis is treated with which of the following surgical options?

Partial penectomy with a 2 cm margin. ***Partial penectomy with a 2 cm margin*** - For **penile cancer** confined to the glans, **partial penectomy** is the standard surgical approach to achieve local control while preserving penile length. - Historically, a **2 cm tumor-free margin** was recommended as the standard of care (reflected in older guidelines and exam questions). - **Modern evidence** suggests that narrower margins of **5-8 mm** are oncologically safe with comparable local control rates, but the **2 cm margin** was the traditional teaching and remains the expected answer for this question context. *Simple circumcision* - **Simple circumcision** is indicated for benign conditions like **phimosis** or **premalignant lesions** (carcinoma in situ), not for invasive cancer. - It does not provide adequate oncological clearance for **invasive penile cancer** and carries a high risk of **local recurrence**. *Partial penectomy with a 4 cm margin* - A **4 cm margin** is excessively radical and would result in unnecessary loss of penile length and function. - Even by historical standards, this exceeds the recommended **2 cm margin** and would cause significant functional and psychological morbidity. *Partial penectomy with inguinal lymph node dissection* - **Inguinal lymph node dissection** is indicated when there is **clinical or radiological evidence of lymph node metastasis** or high-risk pathological features. - Without evidence of nodal involvement, routine prophylactic lymphadenectomy is not performed due to significant morbidity (lymphedema, wound complications). - The question does not specify nodal involvement, making this option unnecessarily aggressive.

Q: A high-riding prostate is indicative of which injury?

Membranous Urethral Injury. ***Membranous Urethral Injury*** - A **high-riding prostate** is a classic sign of **membranous urethral injury**, often resulting from **pelvic fractures**. - The disruption of the **urethra** above the perineal membrane causes the prostate to be displaced superiorly and appear "high." *Extraperitoneal Bladder rupture* - This typically occurs with **pelvic fractures** and involves urine leaking into the **retropubic space**. - While associated with pelvic trauma, it does not directly cause a high-riding prostate; the bladder itself may be ruptured, but the relative position of the prostate is not significantly altered. *Intraperitoneal Bladder Rupture* - This type of rupture usually results from a direct blow to a **full bladder** and involves urine extravasating into the **peritoneal cavity**. - It does not cause a high-riding prostate, as the injury is to the dome of the bladder, not the structures supporting the prostate. *Bulbar Urethral Injury* - A **bulbar urethral injury** usually results from a **straddle injury** and is located in the anterior urethra. - This type of injury does not affect the anatomical position of the prostate, which is posterior and superior to the bulbar urethra.

Q: The Grayhack shunt is established between which of the following?

Corpora cavernosa and saphenous vein. ***Corpora cavernosa and saphenous vein*** - The **Grayhack shunt** is a proximal **cavernosal-venous shunt** that connects the corpus cavernosum to the **great saphenous vein**. - This procedure surgically manages **refractory priapism** by diverting blood away from the trapped penile cavernosal spaces into the systemic venous circulation. - It is performed when distal and proximal corporeal shunts have failed. *Corpora cavernosa and dorsal vein* - This describes the **Barry shunt**, which connects the corpus cavernosum to the **deep dorsal vein**. - The Al-Ghorab shunt (sometimes confused) is actually a **distal corporo-glanular shunt** involving open excision of glans tissue — not a dorsal vein shunt. *Corpora cavernosa and glans* - This describes **distal cavernosal-glanular shunts** such as the **Winter shunt** (percutaneous needle) or **Ebbehoj shunt** (scalpel incision), which create a communication between the corpus cavernosum and the glans penis. - These are **first-line** surgical options for priapism but are distinct from the proximal Grayhack shunt. *Corpora cavernosa and corpora spongiosa* - This describes the **Quackels shunt**, a **proximal cavernosal-spongiosal shunt** connecting the corpora cavernosa to the corpus spongiosum. - Also used for refractory priapism, but anatomically and surgically distinct from the Grayhack (cavernosal-venous) shunt.

Q: Young male with history of trauma having left sided testis swollen and erythematous. Other side normal. What is the diagnosis?

Hematoma. ***Hematoma*** - A history of **trauma** leading to a **swollen and erythematous testis** is highly indicative of a testicular hematoma. Trauma can cause bleeding within the scrotal sac, leading to the observed symptoms. - A hematoma is a localized collection of **blood outside of blood vessels**, which in this case, results from the injury to the testis or surrounding structures. *Torsion* - Testicular torsion typically presents with **sudden, severe pain** and swelling, and can be associated with absent **cremasteric reflex**. While swelling is present, the clear history of trauma points away from spontaneous torsion. - Torsion is an **emergency** caused by the twisting of the spermatic cord, which **cuts off blood supply** to the testis, and usually lacks a direct antecedent trauma. *Carcinoma* - Testicular carcinoma usually presents as a **painless, firm mass** within the testis. Pain can occur if there is hemorrhage within the tumor or rapid growth. - While it can cause swelling, the acute onset and direct association with trauma make carcinoma less likely, as it is a **slowly progressive** condition. *Hernia* - An inguinal hernia typically presents as a **groin bulge** that can extend into the scrotum, and usually reduces with manipulation or lying down. It is often associated with a cough or strain. - While a hernia can cause scrotal swelling, the primary presentation is usually a reducible mass, and the direct link to trauma with associated erythema is not typical for a simple hernia.

Q: Most common anomaly of upper urogenital tract is -

Uretero pelvic junction stenosis. ***Uretero pelvic junction stenosis*** - **Ureteropelvic junction (UPJ) obstruction** is the most common cause of **antenatally detected hydronephrosis**, making it the most frequent anomaly of the upper urogenital tract. - It results from an intrinsic or extrinsic narrowing at the junction of the **renal pelvis** and the **ureter**, impeding urine flow. *Ectopic urethral opening* - This anomaly involves the **urethral opening** being in an abnormal location, such as **hypospadias** or **epispadias** in males, or into the vagina in females. - While relatively common, it is an anomaly of the **lower urogenital tract**, specifically the urethra, not the upper tract. *Ureterocele* - A ureterocele is a **cystic dilation** of the distal part of the ureter as it enters the bladder. - While it can be associated with varying degrees of **upper tract obstruction**, it is not as common as UPJ stenosis. *Ectopic ureter* - An ectopic ureter involves a ureter that drains into an abnormal location other than the **trigone of the bladder**. - This condition is less common than UPJ stenosis and is often associated with a **duplex collecting system**.

Q: In testicular torsion, within what time frame should surgery be performed to save the viability of the testis?

6 hr. ***6 hr*** - Testicular viability is highest when **detorsion** occurs within **6 hours** of symptom onset. - Delay beyond this timeframe significantly increases the risk of **testicular ischemia** and necrosis. *12 hr* - While some viability may remain, the probability of **testicular salvage** decreases substantially after 6 hours. - Testicular function, including **sperm production**, is often compromised even if the testis is saved. *24 hr* - Beyond 12-24 hours, the likelihood of **testicular viability** is very low, and **orchiectomy** (testicle removal) is often necessary. - Prolonged ischemia leads to irreversible **tissue damage** and infarction. *1 week* - After one week, the testis is almost certainly non-viable due to **prolonged ischemia** and necrosis. - This delay would invariably result in the need for **orchiectomy**.

Q: In which condition is the Prehn sign typically positive?

Acute epididymitis. ***Acute epididymitis*** - **Prehn sign** is positive when lifting the scrotal sac alleviates pain, as it reduces pressure on the inflamed epididymis. - This sign is commonly used to differentiate **epididymitis** from **testicular torsion**, where pain typically worsens or remains unchanged with elevation. *Chronic epididymitis* - While potentially painful, **chronic epididymitis** usually presents with persistent, dull pain that is less likely to be acutely relieved by scrotal elevation. - The **Prehn sign** is primarily a diagnostic tool for **acute inflammatory conditions** of the epididymis. *Testicular torsion* - In **testicular torsion**, the pain is often sudden, severe, and typically **not relieved** by elevating the testicle; in fact, it may worsen. - This condition is a **surgical emergency** where blood flow to the testicle is compromised. *Acute scrotal pain due to other causes* - Other causes of **acute scrotal pain**, such as **trauma** or **incarcerated hernias**, generally do not exhibit a positive Prehn sign. - The **Prehn sign** is quite specific to the **inflammatory process** of epididymitis affecting pain perception.

Q: All are true about carcinoma penis except which of the following?

Spreads by blood borne metastasis. ***Spreads by blood borne metastasis*** - Carcinoma penis typically spreads initially via the **lymphatic system** to inguinal lymph nodes. - **Hematogenous spread** is a late event and generally rare, with the most common sites being the lung, liver, and bone. *Leads to erosion of artery* - Local advancement of penile carcinoma can lead to **erosion of penile arteries**, which can cause significant morbidity including bleeding and functional compromise. - This local tissue destruction is a characteristic feature of advanced, uncontrolled penile cancer. *Slowly progressive* - Carcinoma penis is generally a **slowly progressive** malignancy, allowing for early detection and intervention if patients seek medical attention promptly. - The slow growth rate contributes to the fact that many patients present with localized or regionally advanced disease before distant metastases occur. *Most common type is squamous cell carcinoma* - Approximately 95% of penile cancers are **squamous cell carcinomas (SCCs)**, arising from the epithelial cells of the glans or foreskin. - Other rare types include melanoma, basal cell carcinoma, and sarcomas, but SCC vastly predominates.

Q: Circumcision is contraindicated in

Hypospadias. ***Hypospadias*** - In **hypospadias**, the **urethral opening** is located on the underside of the penis, and the foreskin is **essential** for **reconstructive surgery** (urethroplasty) to correct the defect. - Removing the foreskin via circumcision would eliminate this vital tissue, making surgical repair extremely difficult or impossible. - This is the **most absolute contraindication** to circumcision in pediatric urology. *Balanitis* - **Balanitis** is inflammation of the glans penis, often due to poor hygiene or infection. - Circumcision is actually a **treatment** for recurrent balanitis, not a contraindication. - It represents an **indication** for circumcision, not a contraindication. *Paraphimosis* - **Paraphimosis** is a urological emergency where the retracted foreskin becomes trapped behind the glans, causing vascular compromise. - Immediate management involves manual reduction or dorsal slit procedure. - Once the acute condition is resolved, elective circumcision can be performed to prevent recurrence—**not a contraindication**. *Exstrophy of bladder* - **Bladder exstrophy** is a severe congenital anomaly involving the epispadias-exstrophy complex, where the bladder is exposed outside the body. - The foreskin is typically **preserved for penile reconstruction** during complex staged repairs. - While this is also considered a **contraindication to circumcision** in most cases, **hypospadias** remains the **classic and most absolute contraindication** taught in medical education and is the expected answer for this question.

Question 1

A young male presents with a testicular mass on the right side. The AFP is elevated while the HCG is normal. The most appropriate next step is

Accepted Answer

Orchidectomy

Answer

Biopsy

Answer

USG

Answer

Wait and Watch

Question 2

A 45-year-old male presenting with penile cancer extending up to the glans penis is treated with which of the following surgical options?

Accepted Answer

Partial penectomy with a 2 cm margin

Answer

Simple circumcision

Answer

Partial penectomy with a 4 cm margin

Answer

Partial penectomy with inguinal lymph node dissection

Question 3

A high-riding prostate is indicative of which injury?

Accepted Answer

Membranous Urethral Injury

Answer

Extraperitoneal Bladder rupture

Answer

Intraperitoneal Bladder Rupture

Answer

Bulbar Urethral Injury

Question 4

The Grayhack shunt is established between which of the following?

Accepted Answer

Corpora cavernosa and saphenous vein

Answer

Corpora cavernosa and dorsal vein

Answer

Corpora cavernosa and glans

Answer

Corpora cavernosa and corpora spongiosa

Question 5

Young male with history of trauma having left sided testis swollen and erythematous. Other side normal. What is the diagnosis?

Accepted Answer

Hematoma

Answer

Carcinoma

Answer

Hernia

Answer

Torsion

Question 6

Most common anomaly of upper urogenital tract is -

Accepted Answer

Uretero pelvic junction stenosis

Answer

Ureterocele

Answer

Ectopic ureter

Answer

Ectopic urethral opening

Question 7

In testicular torsion, within what time frame should surgery be performed to save the viability of the testis?

Accepted Answer

6 hr

Answer

12 hr

Answer

24 hr

Answer

1 week

Question 8

In which condition is the Prehn sign typically positive?

Accepted Answer

Acute epididymitis

Answer

Chronic epididymitis

Answer

Testicular torsion

Answer

Acute scrotal pain due to other causes

Question 9

All are true about carcinoma penis except which of the following?

Accepted Answer

Spreads by blood borne metastasis

Answer

Leads to erosion of artery

Answer

Slowly progressive

Answer

Most common type is squamous cell carcinoma

Question 10

Circumcision is contraindicated in

Accepted Answer

Hypospadias

Answer

Paraphimosis

Answer

Exostrophy of bladder

Answer

Balanitis

Urology — MCQs

Urology — MCQs

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