Renal Cell Carcinoma Practice Questions

Question 1

The cytogenetics of chromophilic renal cell carcinoma is characterized by:

Accepted Answer

Trisomy 7/17

Answer

Loss of chromosome 3p

Answer

Loss of chromosome 5q3

Answer

Mutant VHL gene

Question 2

Management of RCC less than 4 cm in size:

Accepted Answer

Partial nephrectomy

Answer

Surgery followed by chemotherapy

Answer

Radical nephrectomy

Answer

Chemotherapy

Question 3

A patient has a cerebellar mass, renal tumor, and a family history of similar conditions. Which of the following mutations is most likely present in the family?

Accepted Answer

VHL

Answer

Neurofibromatosis (NF1)

Answer

Tuberous Sclerosis Complex (TSC)

Answer

Li-Fraumeni syndrome

Question 4

Most common type of renal carcinoma is:

Accepted Answer

Clear cell type

Answer

Chromophobe type

Answer

Papillary type

Answer

Collecting duct type

Question 5

What is the best investigation for diagnosis and staging of renal cell carcinoma with thrombus extending into the IVC?

Accepted Answer

CT scan

Answer

Angiography

Answer

Colour doppler imaging

Answer

IVP

Question 6

A patient presents with a renal mass leading to hematuria and flank pain. The histological image below is shown. What is the likely diagnosis?

Accepted Answer

Clear Cell Carcinoma

Answer

Chromophobe Renal Cell Carcinoma (RCC)

Answer

Bellini Duct Carcinoma

Answer

Papillary Cell Carcinoma

Question 7

Treatment of Renal cell carcinoma of less than 4 cm will be-

Accepted Answer

Partial nephrectomy

Answer

Radical nephrectomy

Answer

Radical nephrectomy + postoperative radiotherapy

Answer

Radical nephrectomy + chemotherapy

Question 8

A patient presented with renal cell carcinoma invading the IVC and the renal vein. Which of the following statements is false?

Accepted Answer

IVC involvement indicates inoperability

Answer

Pre op radiotherapy is not essential

Answer

Chest x-ray should be done to rule out pulmonary metastasis.

Answer

Preop biopsy is not necessary

Question 9

Which of the following statements about hypernephroma is true?

Accepted Answer

Not radiosensitive

Answer

May present with rapidly developing varicocele

Answer

Usually an adenocarcinoma

Answer

Arises from the cortex, usually from a pre-existing adenoma

Question 10

All are true about carcinoma penis except which of the following?

Accepted Answer

Spreads by blood borne metastasis

Answer

Leads to erosion of artery

Answer

Slowly progressive

Answer

Most common type is squamous cell carcinoma

Renal Cell Carcinoma — MCQs

Renal Cell Carcinoma — MCQs

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