UPSC-CMS 2012 — Ophthalmology

Q: The most typical clinical presentation of a retinoblastoma is

White reflex in pupil. ***White reflex in pupil*** - The most typical clinical presentation of retinoblastoma is **leukocoria**, or a **white reflex in the pupil**, which occurs when the tumor reflects light. - This symptom is often noticed by parents in photographs (the "cat's eye reflex") or during routine examinations. *Severe pain in the eye* - While retinoblastoma can cause pain in advanced stages, especially with increased **intraocular pressure** or inflammation, it is not the initial or most typical presenting symptom. - **Early retinoblastoma** is usually asymptomatic in terms of pain. *Loss of vision* - Vision loss can occur with retinoblastoma, particularly if the tumor affects the **macula** or becomes large, but it is often detected later than leukocoria. - Young children may not be able to articulate **vision changes**, making leukocoria a more apparent early sign. *Proptosis* - **Proptosis (bulging of the eye)** is an advanced sign of retinoblastoma, indicating significant tumor growth and extension beyond the globe. - It suggests **orbital involvement**, which is characteristic of more aggressive or late-stage disease rather than an initial presentation. [Practice more Ophthalmology PYQs on OnCourse]

Q: The normal range of intraocular pressure (in mmHg) is

10-20. ***10-20*** - The **normal range for intraocular pressure (IOP)** is generally accepted to be between **10 and 20 mmHg**. - Maintaining IOP within this range is crucial for optimal eye health, as deviations can indicate conditions like **glaucoma** or **ocular hypotony**. *15-25* - While 15 mmHg falls within the normal range, **25 mmHg is considered elevated** and potentially indicative of **ocular hypertension** or **glaucoma**. - Sustained pressures above 20-21 mmHg raise concern for **optic nerve damage**. *20-30* - Both 20 mmHg and 30 mmHg are generally considered to be at the **upper end or above the normal range** of IOP. - Pressures in this range significantly increase the **risk of developing glaucoma** and require further evaluation. *5-15* - While 5 mmHg is generally considered low, **15 mmHg is within the normal range**. - An IOP of 5 mmHg or lower for an extended period could indicate **ocular hypotony**, which can lead to various visual problems. [Practice more Ophthalmology PYQs on OnCourse]

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The most typical clinical presentation of a retinoblastoma is

The normal range of intraocular pressure (in mmHg) is