NEET-PG 2018 - Obstetrics and Gynecology Practice Questions

Q: In a woman complaining of AUB following image was seen in endoscopic examination of uterus. What will be the diagnosis?

Leiomyoma. ***Leiomyoma*** - The image shows **well-circumscribed, smooth, rounded masses protruding into the uterine cavity**, which are characteristic of **submucous (intracavitary) leiomyomas (fibroids)** seen on hysteroscopy. - Submucous leiomyomas are benign smooth muscle tumors that project into the endometrial cavity and commonly cause **abnormal uterine bleeding (AUB)** due to increased endometrial surface area, distortion of the endometrial cavity, ulceration of overlying endometrium, and interference with normal uterine contractility. - On **hysteroscopic examination**, they appear as firm, pale, smooth-surfaced masses with overlying endometrium. *Adenomyosis* - Adenomyosis involves the presence of **endometrial tissue within the myometrium**, leading to diffuse uterine enlargement. - On hysteroscopy, it may show a **globally irregular endometrial surface** with small endometrial openings or cystic spaces, but not the discrete, well-circumscribed protruding masses seen in the image. - While it can cause AUB and dysmenorrhea, the appearance is distinctly different from submucous leiomyomas. *Ovarian neoplasm* - Ovarian neoplasms originate in the **ovaries**, which are separate from the uterus. - **Hysteroscopic examination** visualizes only the **endometrial cavity** and cannot directly visualize ovarian pathology. - Ovarian masses do not protrude into the uterine cavity. *Carcinoma of uterus* - Endometrial carcinoma typically presents on hysteroscopy as **irregular, friable, ulcerative, or fungating lesions** with abnormal vascularity and易出血 (easy bleeding). - The **smooth, well-defined, and rounded appearance** with intact overlying mucosa in the image is characteristic of benign leiomyomas, not malignant growths. - Uterine sarcomas are rare and would show more irregular, infiltrative features rather than well-circumscribed masses.

Q: Which drug regimen is given to a pregnant woman with HIV infection?

All of the options. ***All of the options*** - All listed regimens—**Tenofovir disoproxil fumarate (TDF) with emtricitabine (FTC)**, **TDF with lamivudine (3TC)**, and **Abacavir (ABC) with lamivudine (3TC)**—are commonly used and generally safe combinations of **nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs)** in pregnant women with HIV. - The choice of regimen depends on factors such as individual patient characteristics, viral resistance patterns, and potential side effects, but all mentioned regimens are considered **first-line options** in various guidelines for preventing mother-to-child transmission (PMTCT). *Tenofovir disoproxil fumarate with emtricitabine* - This combination is a common and effective **NRTI backbone** for HIV treatment, including in pregnancy, offering good efficacy and a generally favorable safety profile. - It is frequently paired with a third agent (e.g., a **non-nucleoside reverse transcriptase inhibitor (NNRTI)** or an **integrase strand transfer inhibitor (INSTI)**) as part of a highly active antiretroviral therapy (HAART) regimen. *Tenofovir disoproxil fumarate with lamivudine* - This is another widely used and effective **NRTI combination** and is also a recommended backbone for pregnant women with HIV. - While similar to TDF/FTC, some guidelines might prefer one over the other based on specific regional recommendations or drug availability. *Abacavir with lamivudine* - **Abacavir/lamivudine** is a well-established NRTI combination that is safe and effective in pregnancy, provided the mother is **HLA-B*5701 negative** to avoid hypersensitivity reactions. - It is considered a suitable alternative to TDF-containing regimens, especially when there are contraindications or intolerances to TDF.

Q: Which of the following statements about the placenta is correct?

The placenta produces estrogen.. ***The placenta produces estrogen.*** - The **placenta** is an important endocrine organ, producing various hormones including **estrogen** (specifically estriol) and progesterone. - These hormones are crucial for maintaining the pregnancy and supporting fetal development. *The placental artery carries deoxygenated blood from the fetus to the placenta.* - This statement is incorrect as the **umbilical arteries** (not placental arteries) carry **deoxygenated blood and waste products** from the fetus to the placenta. - The **umbilical vein** carries **oxygenated blood and nutrients** from the placenta to the fetus. *The placenta has 2 arteries and 1 vein.* - This describes the typical composition of the **umbilical cord**, not the placenta itself. - The **placenta** is a distinct organ that connects the mother and fetus, facilitating nutrient and gas exchange. *Wharton's jelly is found in the umbilical cord.* - This statement is correct, but the question asks about the **placenta**, not the umbilical cord. - **Wharton's jelly** is a gelatinous substance that protects and supports the blood vessels within the umbilical cord.

Q: What is the most common symptom treated with hormone therapy (HT) in menopausal women?

Hot flashes. ***Hot flashes*** - **Vasomotor symptoms**, including hot flashes and night sweats, are the most frequent and bothersome symptoms experienced by menopausal women, leading them to seek medical attention and hormone therapy. - HT is highly effective in reducing the frequency and severity of hot flashes by stabilizing **thermoregulation** in the hypothalamus. *Breast cancer* - **Breast cancer** is a potential risk associated with hormone therapy, particularly with combined estrogen-progestin therapy, not a symptom treated by HT. - Women with a history of breast cancer or those at high risk are generally advised against HT due to this increased risk. *Endometriosis* - While **estrogen-dependent diseases** like endometriosis can be aggravated by HRT, endometriosis itself is a condition that typically improves after menopause. - HT is not used to treat endometriosis; in certain cases, it might be used to manage menopausal symptoms in women with a history of endometriosis after specific surgical interventions. *Uterine bleeding* - **Uterine bleeding** can be a side effect of hormone therapy, especially when progestin is not adequately balanced with estrogen in women with a uterus. - Abnormal uterine bleeding is a symptom that requires investigation to rule out other causes, and it is not a primary symptom treated by HT.

Q: Identify the X-ray HSG image shown below:

Unicornuate uterus. ***Unicornuate uterus*** - The image distinctly shows a **single, banana-shaped uterine horn** with only one fallopian tube visible, characteristic of a unicornuate uterus resulting from the unilateral arrest of Mullerian duct development. - The contrast material preferentially fills this single cavity, and there is no evidence of a second, rudimentary horn or a bilobed appearance. *Septate uterus* - A septate uterus would show a **normal uterine contour externally** but an **internal septum** dividing the uterine cavity into two cornua. - The image does not show a bilobed uterine cavity with a dividing septum; instead, it demonstrates a single, elongated horn. *Uterus didelphys* - Uterus didelphys involves **two completely separate uteri**, each with its own cervix and vagina, resulting from a complete failure of Mullerian duct fusion. - The image displays a single uterine cavity, not two distinct uterine bodies. *Bicornuate uterus* - A bicornuate uterus is characterized by a **heart-shaped external contour** with a deep fundal indentation and two divergent uterine horns, though often sharing a single cervix and vagina. - The image does not present a prominent fundal indentation or two distinct uterine horns, but rather a single, slender horn.

Q: Based on the provided image, which of the following is the correct diagnosis?

Unicornuate Uterus. ***Unicornuate Uterus*** - The image distinctly shows **only one fallopian tube and one rudimentary uterine horn** on the right side, indicating a unicornuate uterus. - This malformation results from the **incomplete development of one Müllerian duct**, leading to a single, banana-shaped uterine cavity. *Uterus didelphys* - This condition involves **two completely separate uteri**, each with its own cervix and vagina. - The image does not show evidence of two distinct uterine bodies or cervices. *Bicornuate Uterus* - A bicornuate uterus is characterized by **two uterine horns that fuse caudally**, creating a heart-shaped appearance with a shared cervix. - The image clearly lacks the characteristic heart shape and shows only one functional horn. *Septate uterus* - A septate uterus has a **fibrous or muscular septum** dividing the uterine cavity, while the external uterine contour remains normal. - The image does not show a septum or a normal external uterine contour with an internal division; instead, it presents with a single underdeveloped horn.

Q: Which of the following is the most common cause of perforation of uterus in non-pregnant state?

Dilatation and curettage. ***Dilatation and curettage*** - **Dilatation and curettage (D&C)** is the most frequent iatrogenic cause of uterine perforation in the non-pregnant state due to the blind nature of the procedure, especially in cases of uterine anatomical variations or reduced uterine wall integrity. - The risk of perforation is higher in postmenopausal women due to **atrophic, thinned uterine walls**, and in procedures performed for conditions like endometrial hyperplasia or polyps. *Laparoscopy* - While laparoscopic procedures involve inserting instruments into the abdomen, **uterine perforation during laparoscopy itself is rare**, as it usually involves instrumentation *outside* the uterus unless direct uterine manipulation or hysteroscopy is part of the procedure. - Laparoscopy more commonly results in complications like bowel or vascular injury due to trocar insertion, rather than uterine perforation. *IUCD* - **Intrauterine contraceptive device (IUCD)** insertion can cause uterine perforation, but it is less common than with D&C, with an estimated incidence of 1-2 per 1000 insertions. - Perforation during IUCD insertion is typically an immediate event, whereas D&C-related perforations can occur at any stage of the curettage. *Carcinoma Endometrium* - **Endometrial carcinoma** does not typically cause spontaneous uterine perforation, though it can weaken the uterine wall, making it more susceptible to perforation during diagnostic or therapeutic procedures like D&C. - Perforation directly attributable to the carcinoma itself without instrumental intervention is exceedingly rare.

Q: A 16-year-old girl comes to you with primary amenorrhea; on evaluation there is absent breast development, she has a normal stature, her FSH and LH levels are found to be high and she has a karyotype of 46XX. What is the probable diagnosis?

Gonadal dysgenesis. ***Gonadal dysgenesis*** - **Primary amenorrhea** with **absent breast development** and **high FSH/LH** (hypergonadotropic hypogonadism) in a **46,XX individual** with **normal stature** points to **46,XX gonadal dysgenesis** (pure gonadal dysgenesis). - In this condition, the gonads fail to develop properly despite a normal female karyotype, leading to non-functional streak ovaries that fail to produce estrogen, hence the lack of secondary sexual characteristics and elevated gonadotropins due to lack of negative feedback. - Unlike Turner syndrome, patients have normal stature and a normal 46,XX karyotype. *Testicular feminizing syndrome* - Individuals with **complete androgen insensitivity syndrome (CAIS)**, formerly called testicular feminizing syndrome, have a **46,XY karyotype** and develop external female characteristics due to complete androgen resistance. - They present with **primary amenorrhea** but typically have **well-developed breasts** (from peripheral aromatization of testosterone to estrogen) and a blind-ending vagina, which contradicts the absent breast development in this case. *Turner syndrome* - Characterized by a **45,X karyotype** (or variants with mosaicism) and typically presents with **short stature**, primary amenorrhea, and gonadal dysgenesis. - While it causes **primary amenorrhea** and **absent breast development** with high FSH/LH, the **normal stature** and **46,XX karyotype** in this patient rule out Turner syndrome. *Kallmann syndrome* - This condition is characterized by **hypogonadotropic hypogonadism** associated with **anosmia or hyposmia** due to defective GnRH secretion. - Patients present with **low FSH and LH levels**, which contradicts the **high gonadotropin levels** seen in this case.

Q: Shoulder dystocia is managed by all of the following except:-

Fundal pressure by an able nurse. ***Fundal pressure by an able nurse*** - **Fundal pressure** is contraindicated in shoulder dystocia because it can worsen the impaction of the anterior shoulder against the symphysis pubis and potentially lead to uterine rupture or fetal injury. - Applying pressure from above pushes the fetus further into the birth canal obstruction, increasing the risk of **fetal asphyxia** and **brachial plexus injury**. *Woods cork screw method* - This maneuver involves rotating the fetal shoulders by applying pressure to the posterior aspect of the **posterior shoulder**, which often helps to disimpact the anterior shoulder. - It is a recognized and effective technique used to resolve **shoulder dystocia**. *Supra pubic pressure* - **Suprapubic pressure** is applied externally over the maternal suprapubic bone to dislodge the anterior shoulder from behind the symphysis pubis. - This maneuver is often performed first after the initial attempts at fetal head traction and **McRoberts maneuver** to help release the impacted shoulder. *Zavanelli maneuver* - The **Zavanelli maneuver** involves pushing the fetal head back into the uterus and performing an immediate cesarean section. - It is considered a **last-resort maneuver** for severe shoulder dystocia when other techniques have failed, carrying significant risks but sometimes necessary to prevent fetal death.

Q: In Peripartum cardiomyopathy, cardiac failure occurs at:-

Within 5 months after delivery.. ***Within 5 months after delivery.*** - Peripartum cardiomyopathy (PPCM) is defined as the development of **cardiac failure** in the **last month of pregnancy** or within **5 months after delivery**, in the absence of any other identifiable cause. - Among the given options, "within 5 months after delivery" represents the **postpartum component** of the diagnostic timeframe and is the most complete answer. - This time frame is a key diagnostic criterion recognized by major cardiology societies (some recent guidelines extend this to 6 months postpartum). - **Note:** The complete definition includes both antepartum (last month of pregnancy) and postpartum (up to 5 months) periods. *Within 24 months after delivery.* - This timeframe is **too broad** and does not align with the standard diagnostic criteria for PPCM. - While some women may experience ongoing cardiac dysfunction or relapse, the initial diagnosis of PPCM is restricted to within 5 months postpartum. - Extended cardiac issues beyond 5 months may represent persistent PPCM or dilated cardiomyopathy rather than new-onset PPCM. *Within 6 weeks after delivery.* - While many cases of PPCM manifest within **6 weeks postpartum** (the traditional puerperium), this definition is **too restrictive**. - Symptoms can appear up to **5 months after delivery**, and using only 6 weeks would miss a significant proportion of cases. - This period captures the most acute presentations but doesn't encompass the entire recognized diagnostic window. *Within 7 days after delivery.* - The onset within **7 days after delivery** represents only the **immediate postpartum period** and is an overly narrow definition. - PPCM can develop much later in the postpartum period (up to 5 months), making this timeframe inadequate for diagnosis. - Using this restrictive criterion would result in many missed diagnoses.

Question 1

In a woman complaining of AUB following image was seen in endoscopic examination of uterus. What will be the diagnosis?

Accepted Answer

Leiomyoma

Answer

Adenomyosis

Answer

Ovarian neoplasm

Answer

Carcinoma of uterus

Question 2

Which drug regimen is given to a pregnant woman with HIV infection?

Accepted Answer

All of the options

Answer

Tenofovir disoproxil fumarate with emtricitabine

Answer

Tenofovir disoproxil fumarate with lamivudine

Answer

Abacavir with lamivudine

Question 3

Which of the following statements about the placenta is correct?

Accepted Answer

The placenta produces estrogen.

Answer

The placenta has 2 arteries and 1 vein.

Answer

The placental artery carries deoxygenated blood from the fetus to the placenta.

Answer

Wharton's jelly is found in the umbilical cord.

Question 4

What is the most common symptom treated with hormone therapy (HT) in menopausal women?

Accepted Answer

Hot flashes

Answer

Endometriosis

Answer

Uterine bleeding

Answer

Breast cancer

Question 5

Identify the X-ray HSG image shown below:

Accepted Answer

Unicornuate uterus

Answer

Septate uterus

Answer

Uterus didelphys

Answer

Bicornuate uterus

Question 6

Based on the provided image, which of the following is the correct diagnosis?

Accepted Answer

Unicornuate Uterus

Answer

Uterus didelphys

Answer

Bicornuate Uterus

Answer

Septate uterus

Question 7

Which of the following is the most common cause of perforation of uterus in non-pregnant state?

Accepted Answer

Dilatation and curettage

Answer

Laparoscopy

Answer

IUCD

Answer

Carcinoma Endometrium

Question 8

A 16-year-old girl comes to you with primary amenorrhea; on evaluation there is absent breast development, she has a normal stature, her FSH and LH levels are found to be high and she has a karyotype of 46XX. What is the probable diagnosis?

Accepted Answer

Gonadal dysgenesis

Answer

Testicular feminizing syndrome

Answer

Turner syndrome

Answer

Kallmann syndrome

Question 9

Shoulder dystocia is managed by all of the following except:-

Accepted Answer

Fundal pressure by an able nurse

Answer

Woods cork screw method

Answer

Supra pubic pressure

Answer

Zavanelli maneuver

Question 10

In Peripartum cardiomyopathy, cardiac failure occurs at:-

Accepted Answer

Within 5 months after delivery.

Answer

Within 24 months after delivery.

Answer

Within 6 weeks after delivery.

Answer

Within 7 days after delivery.

NEET-PG 2018 — Obstetrics and Gynecology