Immunopathology — MCQs

A 26-year-old systems analyst presents for evaluation of a bee sting allergy. He describes an episode in which he was stung on the forearm by a bee and, within 5 minutes, experienced pruritus, urticaria, and mild wheezing. What is the primary effector cell involved in this type of immediate hypersensitivity reaction?

Xerostomia and enlargement of salivary and lacrimal glands are seen in which condition?

Pathological findings of Sjogren's syndrome include all except:

What is true about hyperacute rejection in renal transplant?

Type 4 hypersensitivity to Mycobacterium tuberculosis antigen may manifest as?

Which type of cells are most dependent on IFN-γ?

A 55-year-old man with idiopathic dilated cardiomyopathy receives a heart transplant. Which of the following is the most likely cause of death in this patient 2 years after transplantation?

A 26-year-old man has had myalgias and a fever for the past week. On physical examination, his temperature is 38.6°C. He has diffuse muscle tenderness, but no rashes or joint pain on movement. Laboratory studies show elevated serum creatine kinase and peripheral blood eosinophilia. Larvae of Trichinella spiralis are present within the skeletal muscle fibers of a gastrocnemius biopsy specimen. Two years later, a chest radiograph shows only a few small calcifications in the diaphragm. Which of the following immunologic mechanisms most likely contributed to the destruction of the larvae?

Which chromosome is defective in De-George syndrome?

Which type of hypersensitivity reaction is mediated by T-lymphocytes and macrophages?