Question 1

Question

A 30-year-old male presents with rapidly progressive renal failure over 3 weeks, haematuria, and red cell casts in urine. Serum creatinine has risen from 1.2 to 7.8 mg/dL within one month. ANCA is positive. The renal biopsy is shown in Image 3. Which of the following statements best describes the cellular composition and origin of the lesion most prominently seen in this biopsy?

Accepted Answer

A. Proliferating parietal epithelial cells of Bowman's capsule and infiltrating macrophages forming a compressive extra-capillary lesion

Answer

B. Proliferating visceral epithelial cells (podocytes) with mesangial expansion forming a segmental sclerosing lesion

Answer

C. Proliferating endothelial cells and mesangial cells with subendothelial immune deposits forming a diffuse proliferative lesion

Answer

D. Proliferating tubular epithelial cells with interstitial fibroblasts forming a periglomerular fibrotic lesion

Immunopathology — MCQs

Immunopathology — MCQs

On this page

Practice by Chapter

Want unlimited practice?