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Immunopathology — MCQs

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418 questions— Page 3 of 42
Q21Easy

In myasthenia gravis, what deposits are found at the neuromuscular junctions?

Q22Easy

Wiskott Aldrich syndrome is associated with all of the following except:

Q23Easy

Which type of immune response is responsible for caseation necrosis in TB?

Q24Medium

Familial amyloidotic polyneuropathy is due to amyloidosis of nerves caused by the deposition of which protein?

Q25Easy

Which CD marker is expressed by NK cells?

Q26Medium

A 52-year-old woman with a history of systemic hypertension and chronic renal failure undergoes kidney transplantation, but the graft fails to produce urine. A renal biopsy is diagnosed as "hyperacute transplant rejection." Graft rejection in this patient is caused primarily by which of the following mediators of immunity and inflammation?

Q27Medium

During heterosexual intercourse, seminal fluid containing HIV contacts vaginal squamous mucosa. Cells capture virions and transport the virus via lymphatics to regional lymph nodes. Within the germinal centers of these lymph nodes, the virions infect CD4+ lymphocytes and proliferate, causing CD4+ cell lysis with release of more virions, which are taken up on the surface of cells having Fc receptors, allowing continued infection by HIV of more CD4+ cells passing through the nodes. Which of the following types of cells is most likely to capture HIV on its surface via Fc receptors?

Q28Medium

Humoral immunodeficiency is suspected in a patient and he is under investigation. Which of the following infections would not be consistent with the diagnosis?

Q29Medium

A 24-year-old woman with leukemia receives an allogeneic bone marrow transplant. Three weeks later, she develops a skin rash and diarrhea. Liver function tests show elevated serum levels of AST and ALT. A skin biopsy discloses a sparse lymphocytic infiltrate in the dermis and epidermis, as well as apoptotic cells in the epidermal basal cell layer. Skin rash and diarrhea in this patient are caused primarily by which of the following cells?

Q30Easy

A woman who is allergic to cats visits a neighbor who has several cats. During the visit, she inhales cat dander, and within minutes, she develops nasal congestion with abundant nasal secretions. Which of the following substances is most likely to produce these findings?

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