Antimicrobials — Flashcards

Flashcard 541: Are NSAIDs useful as anti-inflammatory agents?_____

Answer: Yes

Flashcard 542: Which DNA polymerase inhibiting pyrimidine analog is used to treat both hematologic malignancies and solid tumors?_____

Answer: Gemcitabine

Flashcard 543: Azathioprine/6-MP can result in _____-suppression (-cytopenias)

Answer: myelo

Flashcard 544: Iodoquinol and Paromomycin can be used to treat _____

Answer: Entamoeba Histolytica (which protozoa?)

Flashcard 545: In patients taking ruxolitinib, an important side effect is _____toxicity

Answer: hemato

Extra: Ruxolitinib is a JAK1/JAK2 inhibitor used in the treatment of myelofibrosis and polycythemia vera. Its primary dose-limiting side effects are **hematologic toxicities**, specifically **anemia** and **thrombocytopenia**. While mild LFT elevations can occur, "hematotoxicity" is the high-yield side effect for medical examinations.

Flashcard 546: Which of the platinum analogs is most commonly associated with myelosuppression?

Answer: Carboplatin

Flashcard 547: What neurological side effect is associated with danazol?_____

Answer: Pseudotumor cerebri

Flashcard 548: In addition to increased ulcer healing, bismuth subsalicylate may be used to treat _____ diarrhea

Answer: Traveler's

Flashcard 549: In the setting of acute acetaminophen toxicity, _____ can be used to adsorb acetaminophen

Answer: activated charcoal

Flashcard 550: Fluoroquinolone risk of tendon and cartilage damage is increased with concurrent _____ use

Answer: corticosteroid (ie: prednisone)