Antimicrobials — Flashcards

Flashcard 891: Levetiracetam is a _____ spectrum anti-epileptic

Answer: broad

Flashcard 892: What formula is used to calculate half-life (t1/2) in first-order elimination kinetics?

Answer: t1/2 = (0.693 × Vd) / CL

Extra: Where: - Vd = Volume of Distribution - CL = Clearance - 0.693 = ln(2) In first-order kinetics, half-life is constant and independent of the drug concentration.

Flashcard 893: Taxanes work by preventing the _____ of microtubules

Answer: disassembly

Flashcard 894: Which chemotherapeutic drug is known to cause bladder cancer?_____

Answer: Cyclophosphamide

Flashcard 895: Wilson's disease may be treated with oral _______ or chelating agents (e.g. penicillamine, trientine)

Answer: Zinc