Antimicrobials — Flashcards

Flashcard 141: Mycophenolate mofetil works by inhibiting the proliferation of _____

Answer: lymphocytes

Extra:  https://onlinemeded.org/spa/immunology/immunosuppression/acquire?ref=anki 

Flashcard 142: Sodium stibogluconate is used to treat all forms of _____

Answer: Leishmaniasis

Extra:  https://onlinemeded.org?ref=anki 

Flashcard 143: Metronidazole is a(n) antimicrobial that contains a(n) _____ group allowing it to act as a(n) _____ sink

Answer: nitro

Extra:   Watch Metronidazole [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-other-antibiotics-metronidazole?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki 

Flashcard 144: Metronidazole is used as treatment for which intestinal parasites? _____

Answer: Giardia; Entamoeba histolytica

Extra:    https://onlinemeded.org/spa/microbiology/protozoa/acquire?ref=anki 

Flashcard 145: Nifurtimox and Benznidazole are used to treat _____

Answer: Trypanosoma cruzi

Flashcard 146: Patients should not consume _____ while taking Metronidazole

Answer: alcohol

Extra:    https://onlinemeded.org?ref=anki 

Flashcard 147: Dapsone can be used to treat the blistering skin disorder _____

Answer: Dermatitis Herpetiformis

Extra:    https://onlinemeded.org/spa/dermatology/bullous-diseases/acquire?ref=anki 

Flashcard 148: What drug inhibits dihydrofolate reductase in protozoa? _____

Answer: Pyrimethamine

Extra:   Watch Toxoplasma gondii [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-parasites/videos/medical-microbiology-parasites-protozoa-of-the-cns-toxoplasma-gondii?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/metabolism?ref=anki 

Flashcard 149: In first-order kinetics, a drug infused at a constant rate takes _____ - _____ half-lives to reach steady state

Answer: 4

Extra:   https://onlinemeded.org?ref=anki 

Flashcard 150: In the process of bioactivating -phosphamides, a highly cytotoxic side product known as _____ is released which can cause Hemorrhagic Cystitis

Answer: Acrolein

Extra: Mesna (sodium 2-mercaptoethane sulfonate) and hydration are used to prevent hemorrhagic cystitis by neutralizing acrolein.