Bacteria — Flashcards

Flashcard 731: How do phagocytes in CGD patients kill catalase-negative organisms? _____

Answer: Use H2O2 produced by invading organisms to produce HClO-

Flashcard 732: Which bacteria's spores are commonly found in honey?_____

Answer: Clostridium botulinum

Flashcard 733: Colonies of _____ show a halo of projections, sometimes referred to as "medusa head" appearance

Answer: Bacillus anthracis

Flashcard 734: O2-independent killing in phagocytes is _____ effective than O2-dependent killing

Answer: less

Flashcard 735: Clostridium perfringens binds _____, resulting in watery diarrhea due to destruction of tight junctions

Answer: claudins

Flashcard 736: Which bacterial genetics phenomenon involves the uptake of naked DNA from the environment?

Answer: Transformation

Extra: Transformation is a mechanism of horizontal gene transfer where bacteria take up "naked" DNA from their environment. It was famously demonstrated by Griffith's experiment with Streptococcus pneumoniae. This is distinct from conjugation (cell-to-cell contact) and transduction (viral-mediated).

Flashcard 737: Shigella spp. uses host cell _____ to spread from cell to cell

Answer: actin filaments

Flashcard 738: Staphylococcus aureus is catalase _____

Answer: positive

Flashcard 739: Which toxin of Bordetella pertussis inhibits DNA synthesis in ciliated epithelial cells?_____

Answer: Tracheal toxin

Flashcard 740: What is the etiology of Relapsing Fever?_____

Answer: Borrelia recurrentis