Endocrinology & Diabetes — Flashcards
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What is the management of Cushing's disease if trans-sphenoidal surgery / radiation fails? _____
One clinical feature of Cushing syndrome is abdominal striae which is a result of impaired _____ synthesis, allowing blood vessels to rupture easily
Clinical features of _____ include moon facies, buffalo hump, and truncal obesity due to increased lipogenesis/fat storage, secondary to excess insulin levels (compensatory).
High dose dexamethasone suppression test:\n_____ cortisol + Low/Suppressed ACTH = Adrenal tumor (Adenoma/Carcinoma)
One clinical feature of Cushing syndrome is muscle weakness with _____ extremities
Hint: appearance
One clinical feature seen in women with Cushing's syndrome is _____ as a result of increased androgen levels
One clinical feature of Cushing syndrome is _____, which is a result of decreased osteoblast activity
High dose dexamethasone suppression test: ↓ cortisol = _____
What investigation is used to help differentiate/localise the pathology in Cushing's disease from ectopic ACTH? \n_____
What is the first line management of Cushings DISEASE? 1st Line: _____ 2nd Line: Pituitary radiotherapy OR further surgical removal of the pituitary
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