Endocrinology & Diabetes — Flashcards

Flashcard 131: _____ is used in the management of thyroid storms to inhibit thyroid hormone release

Answer: Lugol's solution (potassium iodide)

Flashcard 132: Pituitary adenomas may present with symptoms of mass effect such as _____, headache and diplopia

Answer: bitemporal hemianopia

Flashcard 133: _____ pituitary adenomas present with reduced libido and infertility/erectile dysfunction in men

Answer: lactotroph (prolactinoma)

Flashcard 134: _____ is used in thyroid storm to inhibit thyroid hormone synthesis and peripheral conversion of T4 to T3.

Answer: Propylthiouracil (PTU)

Extra: PTU has a dual mechanism: 1. Inhibits Thyroid Peroxidase (TPO): blocks synthesis. 2. Inhibits 5'-deiodinase: blocks peripheral conversion of T4 to the more active T3. Note: Methimazole only inhibits synthesis.

Flashcard 135: The management of _____, non-functional (non-secretory) pituitary adenomas is observation only

Answer: asymptomatic

Flashcard 136: Functional Pituitary adenomas result in _____pituitarism

Answer: hyper

Flashcard 137: What investigations can be used to confirm hypercortisolism? _____, 24-hour urinary free cortisol, late-night salivary cortisol

Answer: Low-dose dexamethasone suppression test

Flashcard 138: _____ is the most common pituitary adenoma

Answer: Prolactinoma

Flashcard 139: Thyroid storm TFTs: • TSH: _____ • T3/T4: ↑

Answer: ↓

Flashcard 140: Diagnosis of thyroid storm is based on _____

Answer: clinical features