Immunopathology — Flashcards

Type _____ collagen is targeted by autoantibodies in Goodpasture syndrome

_____ or diffuse nuclear staining may reflect antibodies to chromatin and histones and, occasionally, double-stranded DNA.

_____ is associated with defect at the level of the lymphoid stem cell.

Hint: Type of SCID

Chediak-Higashi syndrome is caused by a defect in the _____ gene, resulting in impaired phagolysosome formation

Asthma pathogenesis: TH2 cells secrete IL-_____ which mediates class switching to IgE

VKC is primarily a type _____ hypersensitivity reaction, but also involves type 4

_____ on the surface of blood cells protects against complement-mediated damage by inhibiting C3 convertase

_____ is a subtype of rhinitis due to a type I hypersensitivity reaction (e.g. to pollen)

Immunodeficiencies with decreased _____-cells tend to produce recurrent bacterial, enterovirus, and Giardia infections

_____ cells are identified by expression of CD3, CD4, CD25, and FOXP3