Hematopathology — Flashcards

Flashcard 341: The expression of _____ is associated with poor prognosis in chronic lymphocytic leukemia (CLL)

Answer: ZAP-70

Flashcard 342: What AML subtype is associated with t(8;21)?_____

Answer: AML M2

Flashcard 343: What are the cellular markers expressed by nasal T-cell lymphoma?_____

Answer: CD56

Flashcard 344: Which blood component has protein C/S and antithrombin?_____

Answer: FFP

Flashcard 345: Convent-girl appearance in peripheral blood smear is described for _____ leukemia

Answer: chronic lymphocytic

Flashcard 346: Which germinal center associated antigens are expressed with Burkitt's lymphoma (non-EBV)?_____

Answer: CD10 and BCL-6 (2)

Flashcard 347: In β-thalassemia minor, the Hb A2 levels usually show an increase up to _____%

Answer: 4–8%

Extra: Normal HbA2 levels are <3.5%. An increase in HbA2 (typically 4–8%) is a diagnostic hallmark of β-thalassemia minor, helping differentiate it from iron deficiency anemia (where HbA2 is characteristically low or normal).

Flashcard 348: Which classes of AML show diffuse positivity for PAS?

Answer: M6 (erythroleukemia) and M7 (megakaryoblastic leukemia)

Flashcard 349: LAP score is usually _____ in the cells of chronic myeloid leukemia

Answer: low

Flashcard 350: What is the most specific test for diagnosing hereditary spherocytosis?_____

Answer: eosin-5-maleimide test