Hematopathology — Flashcards

Flashcard 251: Blasts usually make up _____% of the circulating cells in blast phase of chronic myeloid leukemia

Answer: >20

Flashcard 252: The most common site for extramedullary plasmacytoma is _____

Answer: upper respiratory tract

Flashcard 253: Infantile leukemia is usually _____ for CD10 (CALLA)

Answer: negative

Flashcard 254: If the TT is _____ corrected after adding reptilase then the patient likely has afibrinogenemia

Answer: not

Flashcard 255: Hemophagocytic lymphohistiocytosis is characterized by _____ levels of CXCL9

Answer: elevated

Flashcard 256: Grey platelet syndrome is a disorder involving platelet _____ granules

Answer: alpha

Extra: Grey platelet syndrome (GPS) is characterized by a deficiency of alpha-granules, resulting in large, pale/grey platelets on peripheral smear and a bleeding tendency.

Flashcard 257: Which AML subtype is also known as Naegeli type?

Answer: AML M4

Flashcard 258: Which HLA antigen is associated with Burkitt's lymphoma (non-EBV)?

Answer: HLA-DR7

Flashcard 259: Inv 3 is associated with a _____ prognosis in patients with acute myeloid leukemia (AML).

Answer: poor

Flashcard 260: Which lymphoma is characterized by involvement of a single axial group of lymph nodes (e.g., cervical, mediastinal, para-aortic) and contiguous spread?

Answer: Hodgkin lymphoma

Extra: In contrast to Hodgkin lymphoma, Non-Hodgkin lymphoma (NHL) frequently involves multiple peripheral nodes and spreads in a non-contiguous fashion.