Hematopathology — Flashcards

Flashcard 241: _____ is a marker for Waldenström macroglobulinemia

Answer: MYD88

Flashcard 242: What is the most common bilateral testicular tumors?_____

Answer: Lymphoma

Flashcard 243: Delayed umbilical stump bleeding is characteristic of factor _____ deficiency.

Answer: XIII

Flashcard 244: In Small Lymphocytic Lymphoma (SLL), the absolute lymphocyte count is < _____ per mm³.

Answer: 5,000 (If ≥ 5,000, it is classified as CLL)

Extra: Small Lymphocytic Lymphoma (SLL) and Chronic Lymphocytic Leukemia (CLL) are biologically the same disease. The distinction is based on where the bulk of the disease is located and the peripheral blood count: - **SLL:** Lymphadenopathy + Absolute Lymphocyte Count (ALC) < 5,000/mm³ - **CLL:** ALC ≥ 5,000/mm³ (regardless of lymph node involvement)

Flashcard 245: Activation of the transcription factor _____ is a common event in classical Hodgkin's lymphoma (HL).

Answer: NF-κB

Flashcard 246: Do patients with juvenile CML have philadelphia chromosome?_____

Answer: No

Flashcard 247: What is the anticoagulant used in black coloured ESR vaccutainer?_____

Answer: Citrate

Flashcard 248: What AML subtype is associated with organ infiltration?_____

Answer: AML M5

Flashcard 249: Lymph node biopsy of CLL will show loose aggregates of small lymphocytes and larger activated lymphocytes, commonly referred to as _____ centres

Answer: proliferation

Flashcard 250: Which form (primary or secondary) myelodysplastic syndrome show high risk of transforming to AML?_____

Answer: Secondary/therapy related