Autonomic/CV Drugs — MCQs

A 33-year-old man comes into the urgent care clinic with an intensely itchy rash on the bilateral mid-lower extremities, with a fine linear demarcation approximately an inch above his socks. The rash is arranged in streaks of erythema with superimposed vesicular lesions. The patient states that he recently began hiking in the woods behind his house, but he denies any local chemical exposures to his lower extremities. His vital signs include: blood pressure of 127/76, heart rate of 82/min, and respiratory rate of 12/min. Of the following options, which is the mechanism of his reaction?

An 8-year-old boy is brought to the pediatrician by his parents due to recurrent episodes of wheezing for the last 2 years. He uses a salbutamol inhaler for relief from wheezing, but his symptoms have recently worsened. He often coughs during the night, which awakens him from sleep almost every other day. He is not able to play football because he starts coughing after 10–15 minutes of play. His current physical examination is completely normal and auscultation of his chest does not reveal any abnormal breath sounds. His peak expiratory flow rate (PEFR) is 75% of expected for his age, gender, and height. After a complete diagnostic evaluation, the pediatrician prescribes a low-dose inhaled fluticasone daily for at least 3 months. He also mentions that the boy may require continuing inhaled corticosteroid (ICS) therapy for a few years if symptoms recur after discontinuation of ICS. However, the parents are concerned about the side effects of corticosteroids. Which of the following corticosteroid-related adverse effects is most likely?

A 36 year-old woman presents to the doctor’s office for evaluation of substernal chest pain and a metallic taste in her mouth. The patient has a history of metabolic syndrome and hypothyroidism. She takes levothyroxine daily. The patient’s vital signs are currently stable. On examination, she appears to be in mild discomfort, but is alert and oriented. The abdomen is mildly tender to palpation without guarding. Which of the following is the most appropriate treatment choice based on her history and physical examination?

A 45-year-old Caucasian man is given nitroglycerin for the management of his stable angina. Nitroglycerin given for the rapid relief of acute angina would most likely be given through what route of administration?

A 28-year-old man comes to his general practitioner for a regular checkup. He has had trouble breathing lately with coughing, shortness of breath, and wheezing. Problems first started when he went running (outside), but he is also observing the problems when taking a light walk or resting. As a child, he suffered from atopic dermatitis, just like his father and sister. He also has a history of hay fever. What is the most likely cause of his symptoms?

A 66-year-old gentleman presents to a new primary care physician to establish care after a recent relocation. His past medical history is significant for gout, erectile dysfunction, osteoarthritis of bilateral knees, mitral stenosis, and diabetic peripheral neuropathy. He denies any past surgeries along with the use of any tobacco, alcohol, or illicit drugs. He has no known drug allergies and cannot remember the names of the medications he is taking for his medical problems. He states that he has recently been experiencing chest pain with strenuous activities. What part of the patient's medical history must be further probed before starting him on a nitrate for chest pain?

A 7-year-old boy with asthma is brought to the emergency department because of a 1-day history of shortness of breath and cough. Current medications are inhaled albuterol and beclomethasone. His temperature is 37°C (98.6°F) and respirations are 24/min. Pulmonary examination shows bilateral expiratory wheezing. Serum studies show increased concentrations of interleukin-5. Which of the following is the most likely effect of the observed laboratory finding in this patient?

A 62-year-old man comes to the physician because of tremors in both hands for the past few months. He has had difficulty buttoning his shirts and holding a cup of coffee without spilling its content. He has noticed that his symptoms improve after a glass of whiskey. His maternal uncle began to develop similar symptoms around the same age. He has bronchial asthma controlled with albuterol and fluticasone. Examination shows a low-amplitude tremor bilaterally when the arms are outstretched that worsens during the finger-to-nose test. Which of the following is the most appropriate pharmacotherapy in this patient?

A 28-year-old woman presents to a psychiatrist with a 10-year history of unexplained anxiety symptoms. To date, she has not visited any psychiatrist, because she believes that she should not take medicines to change her emotions or thoughts. However, after explaining the nature of her disorder, the psychiatrist prescribes daily alprazolam. When she comes for her first follow-up, she reports excellent relief from her symptoms without any side-effects. The psychiatrist encourages her to continue her medication for the next 3 months and then return for a follow-up visit. After 3 months, she tells her psychiatrist that she has been experiencing excessive sedation and drowsiness over the last few weeks. The psychiatrist finds that she is taking alprazolam in the correct dosage, and she is not taking any other medication that causes sedation. Upon asking her about any recent changes in her lifestyle, she mentions that for the last 2 months, she has made a diet change. The psychiatrist tells her that diet change may be the reason why she is experiencing excessive sedation and drowsiness. Which of the following is the most likely diet change the psychiatrist is talking about?

A 45-year-old man comes to the physician because of a 3-month history of recurrent headaches. The headaches are of a dull, nonpulsating quality. The patient denies nausea, vomiting, photophobia, or phonophobia. Neurologic examination shows no abnormalities. The physician prescribes a drug that irreversibly inhibits cyclooxygenase-1 and cyclooxygenase-2 by covalent acetylation. Which of the following medications was most likely prescribed by the physician?