Geriatric Psychiatry Practice Questions

Q: Vascular dementia is characterized by which of the following?

All of the above. **Explanation:** Vascular Dementia (VaD) is the second most common cause of dementia after Alzheimer’s disease. It results from brain damage caused by impaired blood flow, such as multiple small infarcts (Multi-infarct dementia) or chronic subcortical ischemia. **Why "All of the above" is correct:** * **Memory Deficit:** Like all forms of dementia, a decline in cognitive function—specifically memory impairment—is a core diagnostic criterion. However, in VaD, memory loss may be less severe or appear later compared to Alzheimer’s, often presenting with more prominent executive dysfunction (e.g., difficulty planning). * **Emotional Lability:** This is a hallmark feature of Vascular Dementia. Patients often exhibit "pseudobulbar affect," characterized by sudden, uncontrollable episodes of crying or laughing. This occurs due to the disruption of cortico-bulbar pathways following vascular insults. **Analysis of Options:** * **Option B & C:** While both are individual characteristics of the disease, they do not represent the complete clinical picture. VaD is a multi-faceted syndrome involving cognitive, neurological, and emotional symptoms. **High-Yield Clinical Pearls for NEET-PG:** 1. **Step-ladder Pattern:** VaD is classically characterized by a **"step-ladder" progression** (sudden functional decline followed by periods of stability), unlike the gradual, continuous decline in Alzheimer’s. 2. **Hachinski Ischemic Score:** A clinical tool used to differentiate VaD from Alzheimer’s. A score **>7** suggests Vascular Dementia. 3. **Focal Neurological Signs:** Patients often present with physical signs like hemiparesis, gait abnormalities, or brisk reflexes, reflecting the underlying stroke/infarct sites. 4. **Risk Factors:** Strongly associated with hypertension, diabetes mellitus, and smoking. Control of these factors is the primary management strategy.

Q: All of the following are examples of cortical dementia except?

Multiple sclerosis. ### Explanation Dementia is broadly classified into **Cortical** and **Subcortical** types based on the primary site of pathology and the clinical presentation. **1. Why Multiple Sclerosis (MS) is the correct answer:** Multiple Sclerosis is primarily a **Subcortical dementia**. It is a demyelinating disease affecting the white matter of the brain and spinal cord. Subcortical dementias are characterized by "executive dysfunction" rather than "cortical" symptoms like aphasia. Clinical features include psychomotor slowing, apathy, forgetfulness, and impaired ability to manipulate acquired knowledge. **2. Analysis of Incorrect Options (Cortical Dementias):** Cortical dementias primarily affect the cerebral cortex (gray matter), leading to early symptoms of **Aphasia** (language deficit), **Agnosia** (failure to recognize objects), **Apraxia** (inability to perform motor tasks), and **Amnesia**. * **Alzheimer’s Disease:** The most common cortical dementia, characterized by amyloid plaques and neurofibrillary tangles. * **Pick’s Disease (Frontotemporal Dementia):** A cortical dementia involving circumscribed atrophy of the frontal and temporal lobes. * **Creutzfeldt-Jakob Disease (CJD):** A rapidly progressive prion disease that causes widespread cortical spongiform changes. **3. NEET-PG High-Yield Pearls:** * **Cortical vs. Subcortical:** If the question mentions **Aphasia**, think Cortical. If it mentions **Movement Disorders** (like tremors or rigidity) or **Psychomotor slowing**, think Subcortical. * **Other Subcortical Dementias:** Parkinson’s disease, Huntington’s disease, Progressive Supranuclear Palsy (PSP), and HIV-associated dementia. * **Reversible Dementias:** Always rule out Vitamin B12 deficiency, Hypothyroidism, and Normal Pressure Hydrocephalus (NPH).

Q: Which of the following statements regarding delirium is true?

Decreased attention. **Explanation:** Delirium is an acute neuropsychiatric syndrome characterized by a transient, reversible decline in cognitive function. The hallmark of delirium is a **disturbance in attention** (reduced ability to direct, focus, sustain, and shift attention) and **awareness** (reduced orientation to the environment). **Why Option D is Correct:** According to DSM-5 criteria, the core feature of delirium is a disturbance in attention and awareness. Patients are easily distracted, unable to follow commands, and show a "clouding of consciousness." This is the most sensitive clinical sign for diagnosing delirium. **Why Other Options are Incorrect:** * **A. Insidious onset:** Delirium is characterized by an **acute onset** (hours to days) and a **fluctuating course** throughout the day (often worsening at night, known as "sundowning"). Insidious onset is typical of Dementia. * **B. Clear consciousness:** In delirium, consciousness is **impaired or clouded**. A "clear sensorium" in the presence of hallucinations or delusions is more suggestive of Schizophrenia or other primary psychotic disorders. * **C. Irreversible:** Delirium is typically **reversible** once the underlying medical cause (e.g., infection, electrolyte imbalance, drug toxicity) is identified and treated. **High-Yield Clinical Pearls for NEET-PG:** * **EEG Findings:** Characteristically shows **generalized slowing** (theta and delta waves). *Exception:* Alcohol/Sedative withdrawal delirium (Delirium Tremens) shows low-voltage fast activity. * **Visual Hallucinations:** These are the most common type of hallucinations in delirium (unlike Schizophrenia, where auditory are more common). * **Drug of Choice:** **Haloperidol** (low-dose) is the preferred antipsychotic for agitation. Avoid benzodiazepines unless the delirium is due to alcohol/sedative withdrawal.

Q: All are features of delirium except?

Loss of memory. **Explanation:** Delirium is an acute, transient, and reversible organic mental syndrome characterized by a **disturbance of consciousness** and a change in cognition. **Why "Loss of Memory" is the correct answer:** While patients with delirium may appear forgetful due to poor attention, **Loss of Memory (Amnesia)** is not a core diagnostic feature of delirium. Memory loss is the hallmark of **Dementia** (a chronic, progressive neurocognitive disorder). In delirium, the primary deficit is **Attention and Awareness**, whereas in dementia, the primary deficit is memory. **Analysis of Incorrect Options:** * **Confusion:** This is a hallmark of delirium. The patient exhibits a "clouding of consciousness," where they cannot think with their customary speed, clarity, and coherence. * **Disorientation:** Delirious patients typically lose their sense of time and place. Disorientation to time is usually the first to appear. * **Hyperactivity:** Delirium is categorized into three motor subtypes: **Hyperactive** (agitation, psychomotor overactivity), **Hypoactive** (lethargy, stupor), and **Mixed**. Hyperactivity is a common clinical presentation, especially in alcohol withdrawal (Delirium Tremens). **NEET-PG High-Yield Pearls:** 1. **Key Diagnostic Feature:** Fluctuating levels of consciousness (waxing and waning) and impaired attention. 2. **EEG Findings:** Characteristically shows **generalized slowing** of background activity (except in Delirium Tremens, where EEG shows fast activity). 3. **Visual Hallucinations:** These are the most common type of hallucinations in delirium (often Lilliputian/microscopic). 4. **Sleep-Wake Cycle:** Reversal of the sleep-wake cycle (daytime somnolence and nighttime agitation/sundowning) is very common.

Q: What is the most common cause of dementia?

Alzheimer’s disease. **Explanation:** **1. Why Alzheimer’s Disease is Correct:** Alzheimer’s disease (AD) is the most common cause of dementia worldwide, accounting for approximately **60–80% of all cases**. It is a neurodegenerative condition characterized by the accumulation of amyloid-beta plaques and tau neurofibrillary tangles. Clinically, it presents with progressive memory loss (especially episodic memory), disorientation, and cognitive decline. **2. Why the Other Options are Incorrect:** * **A. Fronto-temporal dementia (FTD):** While it is a significant cause of dementia in younger patients (under age 65), it is much rarer than AD. It typically presents with prominent personality changes or language deficits rather than early memory loss. * **B. Senile dementia:** This is an outdated, descriptive term rather than a specific pathological diagnosis. It simply refers to dementia occurring in old age. Most cases historically labeled as "senile dementia" are actually Alzheimer’s disease. * **C. Multi-infarct dementia:** Also known as Vascular Dementia, this is the **second most common** cause of dementia (approx. 10–20%). It is characterized by a "step-ladder" pattern of decline and is associated with cardiovascular risk factors and strokes. **3. High-Yield Clinical Pearls for NEET-PG:** * **Most common cause of dementia:** Alzheimer’s Disease. * **Second most common cause:** Vascular Dementia. * **Early sign of AD:** Loss of recent memory (Anterograde amnesia). * **Genetic markers:** APOE-ε4 (risk factor), Presenilin 1 & 2 (early-onset). * **Neurobiology:** Atrophy of the hippocampus and deficiency of Acetylcholine. * **Treatment of choice:** Cholinesterase inhibitors (Donepezil, Rivastigmine) and NMDA antagonists (Memantine).

Q: An 82-year-old female with a history of age-related macular degeneration, hypertension, and hypercholesterolemia presents with a complaint of visual hallucinations. She reports seeing wild animals in her room, which has been occurring for a year since she lost her sight. She acknowledges that the hallucinations are not real. Her MMSE score is 28/30. What is the most likely diagnosis?

Charles-Bonnet Syndrome. ### Explanation **Correct Answer: D. Charles-Bonnet Syndrome** **Why it is correct:** Charles-Bonnet Syndrome (CBS) is characterized by **complex visual hallucinations** in patients with significant **visual impairment** (most commonly age-related macular degeneration, as seen here). * **Key Concept:** The "Deafferentation Hypothesis" suggests that the loss of sensory input leads to spontaneous firing in the visual association cortex. * **Insight:** Crucially, patients maintain **insight** (they know the hallucinations are not real) and have **no cognitive impairment** (MMSE 28/30) or other psychotic symptoms. **Why the other options are incorrect:** * **A. Hyperactive Delirium:** Delirium involves an acute fluctuation in consciousness and attention, often with a physical trigger. This patient has a chronic (one-year) history and is cognitively intact. * **B & C. Vascular Dementia / Alzheimer's Disease:** While dementia can cause hallucinations, the patient’s high MMSE score (28/30) and preserved insight rule out significant cognitive decline. In dementia, hallucinations are usually accompanied by memory loss and executive dysfunction. **High-Yield Clinical Pearls for NEET-PG:** * **Classic Triad:** Visual impairment + Complex visual hallucinations + Preserved insight. * **Hallucination Type:** Usually "Lilliputian" (small people/animals) or vivid, colorful patterns. * **Management:** Reassurance is the first-line treatment. If distressing, low-dose antipsychotics or SSRIs may be used, though evidence is limited. * **Differential:** Unlike Schizophrenia, there are no auditory hallucinations or delusions. Unlike Lewy Body Dementia, there are no parkinsonian features or cognitive fluctuations.

Q: A semiconscious patient with altered sensorium, visual hallucinations, and fragmented delusions is suffering from which of the following disorders?

Delirium. **Explanation:** The clinical presentation described—**altered sensorium (semiconscious), visual hallucinations, and fragmented delusions**—is the classic triad of **Delirium**. 1. **Why Delirium is correct:** Delirium is an acute organic mental disorder characterized by a **clouding of consciousness** (altered sensorium). Key features include a fluctuating course, disorientation, and impairment in attention. While hallucinations and delusions occur, they are typically secondary to the clouded state; visual hallucinations are particularly characteristic of organic etiologies like delirium, whereas auditory hallucinations are more common in functional psychoses. 2. **Why other options are incorrect:** * **Delusion:** This is a symptom (a fixed, false belief), not a diagnosis. In delirium, delusions are "fragmented" or unsystematized, unlike the well-formed delusions seen in delusional disorders. * **Schizophrenia:** This is a functional psychosis characterized by **clear consciousness**. Patients are fully awake and oriented. Hallucinations are predominantly auditory (third-person). * **Mania:** While mania involves heightened arousal and possible delusions/hallucinations, the **sensorium remains clear**. The patient is typically hyper-alert rather than semiconscious. **High-Yield Clinical Pearls for NEET-PG:** * **Delirium vs. Dementia:** Delirium has an acute onset and fluctuating consciousness; Dementia has an insidious onset and clear consciousness (until late stages). * **Hallucinations:** Visual hallucinations are the most common type in organic brain syndromes (Delirium/Withdrawal states). * **EEG Finding:** The most common EEG finding in delirium is **generalized slowing** of background activity (except in Delirium Tremens, where there is low-voltage fast activity). * **Management:** The primary goal is treating the underlying cause; Haloperidol is the drug of choice for symptomatic control of agitation.

Question 1

Vascular dementia is characterized by which of the following?

Accepted Answer

All of the above

Answer

This option is a repetition of the question stem and should be removed.

Answer

Memory deficit

Answer

Emotional lability

Question 2

All of the following are examples of cortical dementia except?

Accepted Answer

Multiple sclerosis

Answer

Alzheimer's disease

Answer

Creutzfeldt Jacob disease

Answer

Pick's disease

Question 3

Which of the following statements regarding delirium is true?

Accepted Answer

Decreased attention

Answer

Insidious onset

Answer

Clear consciousness

Answer

Irreversible

Question 4

All are features of delirium except?

Accepted Answer

Loss of memory

Answer

Confusion

Answer

Disorientation

Answer

Hyperactivity

Question 5

A disease occurring before 65 years of age is termed as:

Accepted Answer

Presenile

Answer

Senile

Answer

Post adolescent

Answer

Post senile

Question 6

What is the most common cause of dementia?

Accepted Answer

Alzheimer’s disease

Answer

Fronto-temporal dementia

Answer

Senile dementia

Answer

Multi-infarct dementia

Question 7

An 82-year-old female with a history of age-related macular degeneration, hypertension, and hypercholesterolemia presents with a complaint of visual hallucinations. She reports seeing wild animals in her room, which has been occurring for a year since she lost her sight. She acknowledges that the hallucinations are not real. Her MMSE score is 28/30. What is the most likely diagnosis?

Accepted Answer

Charles-Bonnet Syndrome

Answer

Hyperactive Delirium

Answer

Vascular Dementia

Answer

Alzheimer's Disease

Question 8

A semiconscious patient with altered sensorium, visual hallucinations, and fragmented delusions is suffering from which of the following disorders?

Accepted Answer

Delirium

Answer

Delusion

Answer

Schizophrenia

Answer

Mania

Question 9

A 60-year-old man is found roaming aimlessly and brought to the hospital. He is unable to tell his address. Blood investigations reveal: Na+ 115 mEq/L, K+ 3.2 mEq/L. Which of the following is the most likely diagnosis?

Accepted Answer

Delirium

Answer

Multi-infarct dementia

Answer

Alzheimer's disease

Answer

Dissociative fugue

Question 10

All of the following are true about dementia except:

Accepted Answer

Loss of long-term memory

Answer

Loss of short-term memory

Answer

Deterioration of personality

Answer

Impaired learning

Geriatric Psychiatry — MCQs

Geriatric Psychiatry — MCQs

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