Community Medicine
2 questionsIndia started 2-dose vaccination strategy for measles, in -
Vaccines are available against which types of meningococcus?
NEET-PG 2013 - Community Medicine NEET-PG Practice Questions and MCQs
Question 701: India started 2-dose vaccination strategy for measles, in -
- A. 2008
- B. 2009
- C. 2010 (Correct Answer)
- D. 2011
Explanation: ***2010*** - India implemented the **two-dose measles vaccination strategy** as part of its Universal Immunization Program starting in **2010**. - This decision was based on recommendations to improve immunity and reduce measles incidence, moving from a single-dose to a more effective **two-dose schedule**. *2008* - While important immunization initiatives were ongoing, the specific policy of a **two-dose measles vaccination strategy** had not yet been introduced in India during 2008. - At this time, the focus was primarily on ensuring high coverage of the **first dose** of measles vaccine. *2009* - The year 2009 saw continued efforts to strengthen the Universal Immunization Program, but the official launch of the **two-dose measles vaccination strategy** in India occurred later. - Discussions and planning for the transition were likely underway, but implementation began in the subsequent year. *2011* - By 2011, the **two-dose measles vaccination strategy** was already being implemented across India, having been introduced in 2010. - This year marked a period of expanding coverage and consolidation of the new 2-dose schedule rather than its initial introduction.
Question 702: Vaccines are available against which types of meningococcus?
- A. Type A
- B. Type B
- C. Type A, B, and C
- D. Type A, B, C, W, and Y (Correct Answer)
Explanation: ***Type A, B, C, W, and Y*** - Vaccines are currently available against **all five major meningococcal serogroups**: A, B, C, W-135, and Y. - **Meningococcal conjugate vaccines (MenACWY)** provide protection against serogroups A, C, W-135, and Y, and are widely used globally. - **Meningococcal B vaccines (MenB)** such as Bexsero and Trumenba specifically target serogroup B, which is a leading cause of meningococcal disease in developed countries. - Combined, these vaccines provide comprehensive coverage against the most epidemiologically important meningococcal serogroups worldwide. *Type A* - While vaccines against **meningococcus type A** do exist (as part of conjugate vaccines), this option is incomplete as it excludes the other important serogroups (B, C, W, Y) for which vaccines are also available. *Type B* - **Type B vaccines** are available and important, particularly in developed countries where serogroup B causes significant disease burden. - However, this option alone is insufficient because vaccines also effectively target other serogroups (A, C, W, Y). *Type A, B, and C* - This option is incomplete because it omits **serogroups W and Y**, for which conjugate vaccines (MenACWY) are readily available and widely used. - The question asks which types vaccines are *available* against, not which are most common, making this an incorrect answer.
Forensic Medicine
4 questionsMiscarriage due to medical negligence is seen under which IPC?
Which traditional method is considered most reliable for personal identification in forensic science?
According to which section of the Indian Penal Code (IPC) is the punishment for murder prescribed?
What is the penalty for violating the Dowry Prohibition Act?
NEET-PG 2013 - Forensic Medicine NEET-PG Practice Questions and MCQs
Question 701: Miscarriage due to medical negligence is seen under which IPC?
- A. Sec 304A IPC (Correct Answer)
- B. Sec 310 IPC
- C. Sec 312 IPC
- D. Sec 314 IPC
Explanation: ***Sec 304A IPC*** - This section specifically deals with **causing death by negligence** (rash or negligent acts not amounting to culpable homicide). - **Medical negligence causing miscarriage** falls under this section as it involves an unintentional harm due to negligent medical practice. - This is the appropriate section when there is no voluntary intent to cause miscarriage, but harm results from professional negligence. *Sec 312 IPC* - This section deals with **voluntarily causing miscarriage**, requiring intentional/voluntary act. - It applies when a person **intentionally** causes a woman to miscarry (criminal abortion). - Medical **negligence** does not constitute a voluntary act in the legal sense, so Sec 312 does not apply to negligence cases. *Sec 310 IPC* - This section is related to **thuggee**, defining someone who habitually commits robbery or child-stealing by murder. - It has no relevance to medical negligence or miscarriage. *Sec 314 IPC* - This section deals with **death caused by an act done with intent to cause miscarriage**. - It applies when an intentional act to cause miscarriage results in the death of the woman. - This requires criminal intent, not negligence.
Question 702: Which traditional method is considered most reliable for personal identification in forensic science?
- A. Gustafson's method
- B. Anthropometry
- C. DNA profiling
- D. Galton method (Correct Answer)
Explanation: ***Galton method*** - The **Galton method**, which refers to **fingerprint analysis**, is considered a highly reliable traditional method for personal identification due to the uniqueness and permanence of fingerprints. - No two individuals, even identical twins, have been found to have the exact same **fingerprint patterns**, making it a robust identifier. *Gustafson's method* - **Gustafson's method** is a technique used for **age estimation based on dental changes**, not for definitive personal identification. - While it provides an estimate of age, it cannot uniquely identify an individual. *DNA profiling* - **DNA profiling** is indeed the most reliable method for personal identification in modern forensic science, but it is not considered a "traditional" method. - The question specifically asks for a **traditional method**, distinguishing it from newer genetic techniques. *Anthropometry* - **Anthropometry** involves the measurement of the **human body and its parts**, often used for classification or to establish demographic profiles. - It is not reliable for unique personal identification as many individuals share similar physical measurements.
Question 703: According to which section of the Indian Penal Code (IPC) is the punishment for murder prescribed?
- A. Sec 301 IPC
- B. Sec 300 IPC
- C. Sec 302 IPC (Correct Answer)
- D. Sec 304 IPC
Explanation: ***Sec 302 IPC*** - This section of the Indian Penal Code explicitly prescribes the **punishment for murder**, which can include death or life imprisonment. - While other sections define murder or deal with related offenses, Section 302 specifically addresses the **consequences** for committing murder. *Sec 301 IPC* - This section deals with **culpable homicide by causing death of person other than person whose death was intended**. - It specifies that if a person commits culpable homicide intending to cause the death of one person, but instead causes the death of another, they should be punished as if they had caused the death of the person they intended to kill. *Sec 300 IPC* - This section defines what constitutes **murder** under the Indian Penal Code. - It outlines the specific circumstances and intentions that elevate culpable homicide to the offense of murder. *Sec 304 IPC* - This section prescribes the **punishment for culpable homicide not amounting to murder**. - It specifies different levels of punishment based on the intention or knowledge of the offender, distinguishing it from murder.
Question 704: What is the penalty for violating the Dowry Prohibition Act?
- A. 30000 Rs and 7 years
- B. Life imprisonment
- C. Imprisonment for 10 years
- D. 15000 Rs and 5 years (Correct Answer)
Explanation: ***15000 Rs and 5 years*** - The **Dowry Prohibition Act of 1961** (as amended) stipulates that any person giving or taking dowry, or abetting the giving or taking of dowry, shall be punishable with imprisonment for a term which shall **not be less than five years** and with a fine which shall **not be less than fifteen thousand rupees** or the amount of the value of such dowry, whichever is more. - This represents the **minimum prescribed penalty** for offenses under Section 3 of the Act. *30000 Rs and 7 years* - While dowry-related offenses can lead to significant penalties, a flat fine of **30,000 Rs** and an imprisonment of **7 years** is not the standard or minimum penalty outlined in the **Dowry Prohibition Act**. - The minimum fine is **15,000 Rs or the dowry amount, whichever is more**, and the minimum imprisonment is **five years**, not seven. *Life imprisonment* - **Life imprisonment** is typically reserved for very severe crimes, and while dowry-related deaths can lead to such severe penalties under **Section 304B IPC for dowry death**, violating the general provisions of the **Dowry Prohibition Act** itself (giving or taking dowry under Section 3) does not directly carry a penalty of life imprisonment. - This option misrepresents the direct penalty for dowry prohibition violations under the Act. *Imprisonment for 10 years* - Imprisonment for **10 years** is not the prescribed minimum or standard penalty for violating the **Dowry Prohibition Act** under Section 3 for giving or taking dowry. - The **minimum imprisonment is five years**, with potential for longer sentences depending on the specific circumstances and judicial discretion.
Microbiology
1 questionsPatient came from Nagaland and shows positive test with OXK antigen. Diagnosis is?
NEET-PG 2013 - Microbiology NEET-PG Practice Questions and MCQs
Question 701: Patient came from Nagaland and shows positive test with OXK antigen. Diagnosis is?
- A. Trench fever
- B. Scrub typhus (Correct Answer)
- C. Endemic typhus
- D. Epidemic typhus
Explanation: ***Scrub typhus*** - A **positive Weil-Felix test** for the **OXK antigen** is highly suggestive of scrub typhus, particularly if the patient is from an endemic region like Nagaland. - Scrub typhus is caused by **_Orientia tsutsugamushi_**, transmitted by **chiggers** (larval mites), often presenting with fever and an **eschar**. *Trench fever* - Caused by **_Bartonella quintana_** and transmitted by the **human body louse**. - It does not typically show a positive Weil-Felix test for the OXK antigen. *Endemic typhus* - Also known as **murine typhus**, it is caused by **_Rickettsia typhi_** and transmitted by **fleas** (e.g., rat flea). - While it causes a positive Weil-Felix test, it usually involves the **OX19 antigen**, not OXK. *Epidemic typhus* - Caused by **_Rickettsia prowazekii_** and transmitted by the **human body louse**. - It yields a positive Weil-Felix test for the **OX19 and OX2 antigens**, but typically not for OXK.
Obstetrics and Gynecology
1 questionsWhich vaccine is contraindicated in pregnancy?
NEET-PG 2013 - Obstetrics and Gynecology NEET-PG Practice Questions and MCQs
Question 701: Which vaccine is contraindicated in pregnancy?
- A. Cholera vaccine
- B. Typhoid vaccine
- C. Meningococcal vaccine
- D. Measles vaccine (Correct Answer)
Explanation: ***Measles vaccine*** - The measles vaccine is a **live attenuated vaccine**, which carries a theoretical risk of causing infection in the fetus. - Live vaccines are generally **contraindicated during pregnancy** due to this potential risk of congenital infection. *Cholera vaccine* - The cholera vaccine is generally considered **safe during pregnancy** if indicated, especially for travel to endemic areas. - While administration in pregnancy should be based on risk-benefit, it is not consistently contraindicated like live vaccines. *Typhoid vaccine* - Both inactivated and live attenuated typhoid vaccines are available; the **inactivated (killed) vaccine** is generally preferred if vaccination is necessary during pregnancy. - The risks of the disease usually outweigh the vaccine risks, and it is not a universal contraindication. *Meningococcal vaccine* - **Meningococcal vaccines** are generally considered safe and can be administered during pregnancy if there is a significant risk of exposure or during outbreaks. - The benefits of maternal and potential fetal protection from meningococcal disease outweigh theoretical risks.
Pharmacology
2 questionsWhich of the following drugs can cause thyroid dysfunction?
Which of the following drugs has not been withdrawn from the Indian market for safety reasons?
NEET-PG 2013 - Pharmacology NEET-PG Practice Questions and MCQs
Question 701: Which of the following drugs can cause thyroid dysfunction?
- A. Amiodarone (Correct Answer)
- B. Ampicillin
- C. Ibutilide
- D. Acyclovir
Explanation: ***Amiodarone*** - **Amiodarone** is known to cause both **hypothyroidism** and **hyperthyroidism** due to its high iodine content and direct toxic effects on the thyroid gland. - Its effects can persist for months after discontinuation due to its **long half-life** and accumulation in tissues. *Ampicillin* - **Ampicillin** is an antibiotic that generally does not directly affect thyroid function. - Its primary mechanism of action involves inhibiting **bacterial cell wall synthesis**, with no known significant endocrine side effects. *Ibutilide* - **Ibutilide** is an antiarrhythmic drug used for recent-onset atrial fibrillation or flutter. - It works by blocking potassium channels and has no recognized association with thyroid dysfunction. *Acyclovir* - **Acyclovir** is an antiviral medication used to treat herpes virus infections. - Its mechanism of action involves inhibiting viral DNA replication and it is not known to impact thyroid hormone synthesis or metabolism.
Question 702: Which of the following drugs has not been withdrawn from the Indian market for safety reasons?
- A. Gatifloxacin
- B. Cotrimoxazole (Correct Answer)
- C. Phenformin
- D. Rofecoxib
Explanation: ### Cotrimoxazole - Cotrimoxazole, a combination of **trimethoprim and sulfamethoxazole**, remains a widely used and available antibiotic in India [1], [2]. - It treats various bacterial infections, including **urinary tract infections** and respiratory infections, and has not been withdrawn for safety reasons [1]. ### Gatifloxacin - **Gatifloxacin** was withdrawn from the Indian market due to concerns about **severe glycemic disturbances**, including both hypo- and hyperglycemia. - These side effects posed significant risks, especially in patients with diabetes or those predisposed to blood sugar fluctuations. ### Rofecoxib - **Rofecoxib**, an NSAID, was withdrawn globally, including from India, due to an increased risk of **cardiovascular events** such as heart attack and stroke. - Its selective inhibition of COX-2 was found to disturb the balance of prostaglandins, leading to adverse cardiovascular outcomes. ### Phenformin - **Phenformin**, an oral antidiabetic drug, was withdrawn from the Indian market due to its association with a high incidence of **lactic acidosis**, a severe and often fatal metabolic complication. - This serious side effect made its risk-benefit profile unacceptable for continued use.