NEET-PG 2012 Practice Questions

Q: What is the forensic method of identification that utilizes lip prints?

Cheiloscopy. ***Cheiloscopy*** - **Cheiloscopy** is the scientific study of lip prints for human identification, based on the unique patterns of furrows on the human lips. - These patterns are considered individual and permanent, making them useful in forensic investigations. *Dactylography* - **Dactylography** is the study of fingerprints, which involves analyzing the unique patterns of ridges and furrows on the fingertips for identification. - It is one of the most widely used and reliable methods for personal identification in forensic science, but does not involve lip prints, *Poroscopy* - **Poroscopy** is a forensic technique that involves the examination of the pores on the ridges of fingerprints. - It is used to individualize fingerprints when there is insufficient ridge detail, but it focuses on pores, not lip prints. *Trichology* - **Trichology** is the scientific study of hair and scalp. - In forensics, it involves analyzing hair samples to determine characteristics such as origin, race, and presence of toxins, but not lip prints.

Q: In medical negligence cases, what is the primary role of the plaintiff?

Files case in civil court. ***Files case in civil court*** - The **plaintiff** is the party who initiates a lawsuit, claiming to have been harmed by the actions of another party. - In medical negligence cases, this typically involves someone who alleges injury due to substandard medical care and seeks **compensation** through the legal system. - Filing the case in civil court is the **primary and defining role** of the plaintiff. *Acts as defender* - The **defender** (or defendant) is the party against whom a lawsuit is brought, and they are responsible for responding to the plaintiff's claims. - In medical negligence, the healthcare provider accused of negligence would be the defender. *Gives judgement* - Giving judgment is the function of the **court** or judge and is a neutral adjudication of the facts and application of the law. - The plaintiff's role is to present their case and evidence to persuade the court, not to issue the final decision. *Issues summons to defendant* - Issuing summons is a **court function**, not the plaintiff's role. - The court issues summons after the plaintiff files the case, directing the defendant to appear and respond to the allegations.

Q: La facies sympathique is seen in ?

Hanging. ***Hanging*** - **La facies sympathique** is a term used to describe the facial appearance in cases of **hanging**, characterized by a serene or peaceful look often associated with venous congestion rather than extreme distress. - This appearance is due to the obstruction of venous return from the head while arterial supply continues for a short period, leading to a relatively natural facial expression. *Strangulation* - **Strangulation** typically results in a more dramatic and distressed facial appearance, often with prominent signs of struggle, petechial hemorrhages, and cyanosis. - The compression of both arteries and veins, along with the trachea, leads to rapid and severe cerebral anoxia and overt signs of asphyxia. *Myocardial insufficiency* - **Myocardial insufficiency** (heart failure) usually presents with signs of impaired circulation, such as pallor, cyanosis (especially acrocyanosis), edema, and shortness of breath, but not a specific "sympathetic facies." - The facial expression would more likely reflect distress from dyspnea or discomfort rather than a serene appearance. *Railway accident* - Fatalities from **railway accidents** typically involve severe trauma, disfigurement, and extensive injuries to the head and body. - The facial appearance in such cases would be consistent with massive blunt force trauma, lacerations, or crush injuries, which are inconsistent with "la facies sympathique."

Q: Gastric lavage is contraindicated in which of the following?

Kerosene poisoning. ***Kerosene poisoning*** - Gastric lavage is contraindicated in **kerosene poisoning** due to the high risk of **aspiration pneumonitis**. - Kerosene is a **hydrocarbon**, and aspiration of even small amounts can cause severe lung damage. *Arsenic poisoning* - **Gastric lavage** can be performed in arsenic poisoning, especially if the ingestion occurred recently, to remove unabsorbed toxin. - Activated charcoal is less effective for arsenic, making lavage a more relevant intervention in acute settings. *Organophosphorus Poisoning* - Gastric lavage is generally recommended within an hour of ingestion for **organophosphorus poisoning** to remove the toxic substance. - This helps reduce systemic absorption and mitigate the severe **cholinergic crisis** caused by these agents. *Dhatura poisoning* - **Gastric lavage** is indicated in dhatura poisoning, particularly if presenting within a few hours of ingestion, to remove unabsorbed **atropine-like alkaloids**. - This helps in reducing the **anticholinergic effects** and improving patient outcomes.

Q: Muttering delirium is seen with: NEET 13

Datura. ***Datura*** - **Datura poisoning** is characterized by an **anticholinergic toxidrome**, which includes central nervous system effects like **muttering delirium, hallucinations**, and disorientation. - The patient exhibits features like **dilated pupils, dry mouth, flushed skin**, and **tachycardia** due to the blockage of muscarinic acetylcholine receptors. *Castor oil plant* - The **castor oil plant** contains **ricin**, a potent toxin that causes **gastrointestinal symptoms** (nausea, vomiting, abdominal pain, bloody diarrhea) and eventually multi-organ failure. - It does not typically cause the central nervous system effects like **muttering delirium** seen with Datura poisoning. *Cocaine (stimulant)* - **Cocaine** is a central nervous system stimulant that causes **euphoria, agitation, paranoia, dilated pupils**, and **tachycardia**. - While it can cause psychosis, the specific **muttering delirium** is not its hallmark presentation; instead, it is associated with a hyperadrenergic state. *Monkshood (Aconitum)* - **Monkshood** contains **aconitine**, a neurotoxin that primarily affects cardiac and neurological function, causing **paresthesias, muscle weakness, bradycardia**, and potentially fatal arrhythmias. - It does not typically cause the **muttering delirium** with features of an anticholinergic syndrome.

Q: When is the prozone phenomenon seen?

Antibody excess to antigen. ***Antibody excess to antigen*** - The **prozone phenomenon** occurs when there is a significant **excess of antibodies** relative to the antigen, leading to inhibition of lattice formation. - In this state, too many antibodies bind to individual antigen sites, preventing cross-linking and thus inhibiting visible **agglutination** or **precipitation**. *Same concentration of antibody and antigen* - This scenario typically represents the **zone of equivalence**, where optimal lattice formation and visible reaction (agglutination or precipitation) occur. - It is where the concentrations of antibody and antigen are balanced, leading to maximum complex formation. *In antigen excess to antibody* - This situation is known as the **postzone phenomenon**, where an excess of antigen prevents the formation of stable antibody-antigen complexes. - The antigen saturates the limited antibody sites, resulting in no or minimal visible reaction. *Hyperimmune reaction* - A hyperimmune reaction refers to an **exaggerated immune response**, often resulting from repeated exposure to an antigen. - While it involves high antibody levels, it is a clinical state rather than a specific phenomenon describing antibody-antigen ratios in *in vitro* tests.

Q: Smallpox belongs to which genus of poxviruses?

Orthopoxvirus. ***Orthopoxvirus*** - **Smallpox** (caused by the **variola virus**) is a classic member of the Orthopoxvirus genus. - This genus includes other human pathogens like **monkeypox** and vaccinia virus (used in the smallpox vaccine). *Parapoxvirus* - This genus includes viruses like **Orf virus** (causing contagious pustular dermatitis in sheep and goats) and pseudocowpox virus. - These viruses typically cause milder, localized lesions and are morphologically distinct from orthopoxviruses. *Capripoxvirus* - This genus includes viruses primarily affecting livestock, such as **lumpy skin disease virus**, sheep pox virus, and goat pox virus. - They cause systemic infections and skin lesions in their respective animal hosts and are not associated with human disease like smallpox. *Leporipox virus* - This genus includes viruses that primarily infect rabbits and hares, such as **myxoma virus** and fibroma virus. - These viruses typically cause tumors or severe systemic disease in their rabbit hosts and are not known to infect humans.

Q: Which of the following statements about vinca alkaloids is true?

Inhibits mitotic spindle. ***Inhibits mitotic spindle*** - **Vinca alkaloids** (e.g., vincristine, vinblastine) exert their cytotoxic effects by binding to **tubulin**, thereby inhibiting its polymerization into microtubules. - This disruption prevents the formation of the **mitotic spindle**, arresting cells in metaphase and leading to apoptosis. *Enhances polymerization of tubulin* - This statement describes the mechanism of action of **taxanes** (e.g., paclitaxel), which stabilize microtubules and prevent their depolymerization. - Vinca alkaloids, in contrast, **inhibit** tubulin polymerization, preventing microtubule assembly. *Inhibits topoisomerase I* - Inhibition of **topoisomerase I** is the mechanism of action for drugs like **irinotecan** and **topotecan**. - These agents cause single-strand breaks in DNA, which is distinct from the microtubule disruption caused by vinca alkaloids. *Inhibits topoisomerase II* - Drugs like **etoposide** and **teniposide** work by inhibiting **topoisomerase II**, leading to double-strand DNA breaks. - This mechanism is different from the disruption of microtubule dynamics seen with vinca alkaloids.

Q: Which of the following antineoplastic drugs SHOULD NOT be given by rapid IV infusion?

Cisplatin. ***Cisplatin*** - **Cisplatin** is highly nephrotoxic and emetogenic; rapid IV infusion can exacerbate these adverse effects, leading to severe renal damage and intractable nausea/vomiting. - It typically requires **prolonged infusion times** (e.g., 6-8 hours) with extensive pre- and post-hydration to reduce kidney toxicity and ensure patient tolerance. *Cyclophosphamide* - While cyclophosphamide can cause **hemorrhagic cystitis**, this is managed by adequate hydration and mesna, and its infusion rate is generally not as critically prolonged as cisplatin's. - It is often administered as a **relatively quick IV infusion** over 30-60 minutes, emphasizing hydration. *Bleomycin* - **Bleomycin** is known for pulmonary toxicity and hypersensitivity reactions, but these are not primarily linked to its infusion rate. - It is commonly given via **slow IV push or short infusion**, sometimes with a test dose to assess for hypersensitivity. *Cytosine arabinoside* - **Cytosine arabinoside** can cause myelosuppression and cerebellar toxicity, but these toxicities are not typically exacerbated by a rapid infusion rate. - It is often administered via a **continuous infusion** over several days or as a rapid IV bolus.

Q: What is the first aid treatment for acid contact with the skin?

Wash with copious amounts of water. ***Wash with copious amounts of water*** - The primary first aid for acid contact with the skin is immediate and prolonged **irrigation with copious amounts of water**. This helps to dilute the acid and wash away residual chemicals, minimizing tissue damage. - Flushing should continue for at least **20-30 minutes** or until medical help arrives, even if the pain subsides, to ensure thorough removal of the corrosive agent. *Wash with strong alkali* - Using a strong alkali to neutralize an acid burn can lead to an **exothermic reaction**, generating significant heat and causing further tissue damage. - This approach carries a high risk of worsening the chemical burn and should be strictly avoided. *Refer to higher centre* - While referral to a higher center may be necessary for severe burns, it is not the **immediate first aid step**. Delaying initial management to seek advanced care can worsen the burn. - **Immediate irrigation** is crucial to prevent further chemical injury and should precede any transfer decisions. *Wash with mild alkali agent* - Similar to strong alkalis, even a mild alkali agent can cause an **exothermic reaction** when mixed with acid on the skin, potentially increasing tissue damage rather than mitigating it. - The most effective and safest approach is **dilution with water**, not neutralization with bases.

Question 1

What is the forensic method of identification that utilizes lip prints?

Accepted Answer

Cheiloscopy

Answer

Trichology

Answer

Dactylography

Answer

Poroscopy

Question 2

In medical negligence cases, what is the primary role of the plaintiff?

Accepted Answer

Files case in civil court

Answer

Acts as defender

Answer

Gives judgement

Answer

Issues summons to defendant

Question 3

La facies sympathique is seen in ?

Accepted Answer

Hanging

Answer

Strangulation

Answer

Myocardial insufficiency

Answer

Railway accident

Question 4

Gastric lavage is contraindicated in which of the following?

Accepted Answer

Kerosene poisoning

Answer

Organophosphorus Poisoning

Answer

Dhatura poisoning

Answer

Arsenic poisoning

Question 5

Muttering delirium is seen with: NEET 13

Accepted Answer

Datura

Answer

Castor oil plant

Answer

Cocaine (stimulant)

Answer

Monkshood (Aconitum)

Question 6

When is the prozone phenomenon seen?

Accepted Answer

Antibody excess to antigen

Answer

Same concentration of antibody and antigen

Answer

Hyperimmune reaction

Answer

In antigen excess to antibody

Question 7

Smallpox belongs to which genus of poxviruses?

Accepted Answer

Orthopoxvirus

Answer

Leporipoxvirus

Answer

Capripoxvirus

Answer

Parapoxvirus

Question 8

Which of the following statements about vinca alkaloids is true?

Accepted Answer

Inhibits mitotic spindle

Answer

Enhances polymerization of tubulin

Answer

Inhibits topoisomerase I

Answer

Inhibits topoisomerase II

Question 9

Which of the following antineoplastic drugs SHOULD NOT be given by rapid IV infusion?

Accepted Answer

Cisplatin

Answer

Cyclophosphamide

Answer

Cytosine arabinoside

Answer

Bleomycin

Question 10

What is the first aid treatment for acid contact with the skin?

Accepted Answer

Wash with copious amounts of water

Answer

Wash with strong alkali

Answer

Refer to higher centre

Answer

Wash with mild alkali agent

NEET-PG 2012

Dental

Forensic Medicine

Microbiology

Pharmacology

Surgery