Primary Immunodeficiency Disorders — MCQs

Given the immunologic abnormalities of normal serum IgG, normal serum IgA, normal serum IgM, decreased T-cell function, and decreased parathyroid function, which clinical presentation is most likely?

A 5-year-old boy has recurrent infections, low platelet count, and rash as shown below. What is the likely diagnosis?

Which one of the following statements is false regarding chronic granulomatous disease?

Which of the following statements about Wiskott-Aldrich syndrome is false?

A 6-month-old male infant presents with recurrent severe bacterial infections with encapsulated organisms (Streptococcus pneumoniae and Haemophilus influenzae). Laboratory findings reveal profound deficiency of all immunoglobulin classes (IgG, IgA, IgM) with absent mature B cells in peripheral blood. The most likely diagnosis is:

A child presented to the casualty department with fever, unconsciousness, and papilledema. What is the next step?

A 4-year-old admitted in ward with pneumonia. He develops sudden onset of breathlessness. What is the next step in management?

Which is true about an infant with failure to thrive and the following findings?

Which of the following are neonatal complications of maternal diabetes during pregnancy? I. Hyperbilirubinemia II. Hypocalcemia III. Cardiomyopathy IV. Hypoglycemia Select the correct answer using the code given below :

A 2.5-year-old boy is brought to the nutrition clinic. He was born at term with a birth weight of 3.0 kg. His mother reports that since weaning he has been fed almost exclusively on a maize-based porridge with minimal animal protein or legumes. On examination, he weighs 9.8 kg and has a height of 82 cm. He has bilateral pitting oedema up to the ankles, generalised skin changes with areas of hyperpigmentation and hypopigmentation, and hair that shows alternating light and dark bands. Serum albumin is 1.8 g/dL. Haemoglobin is 8.2 g/dL. Stool microscopy shows no parasites. Which of the following biochemical profiles is most consistent with this child's nutritional disorder?