Renal Pathology — MCQs

Which of the following statements regarding Wilms tumor is true?

What is the cause of a large kidney in chronic renal failure (CRF)?

Which type of glomerulonephritis is least likely to cause chronic renal failure?

A 3-year-old boy is admitted to the hospital with signs of acute renal failure. Radiologic studies reveal that the boy has bilateral masses involving both kidneys. Examination of biopsy material confirms the diagnosis of Wilms tumor. Which of the following gene mutations is the most common in Wilms tumor?

Periglomerular fibrosis is considered typical of:

What is the most common type of renal cell carcinoma (RCC) associated with dialysis?

What is the major cell type involved in interstitial nephritis?

A 29-year-old man with no significant past medical history presents with acute onset hemoptysis. On physical examination, his vital signs are: temperature 37°C, pulse 83/min, respirations 28/min, and blood pressure 150/95 mm Hg. A chest radiograph reveals bilateral fluffy infiltrates. Microscopic examination of a transbronchial lung biopsy shows focal necrosis of alveolar walls accompanied by significant intra-alveolar hemorrhage. Two days later, he develops oliguria, with a serum creatinine level of 2.9 mg/dL and urea nitrogen of 31 mg/dL. Which of the following antibodies is most likely involved in the pathogenesis of his condition?

Physical examination of a two-year-old child reveals a large abdominal mass. CT studies show that the mass arises in the kidney. Which of the following is most likely a distinctive feature of this lesion?

Necrotizing papillitis is seen in which of the following conditions?