Renal Pathology — MCQs

A 46-year-old woman has had worsening malaise for the past 36 hours. Her urine output is markedly diminished, and it has a cloudy brown appearance. On examination, she has periorbital edema. Laboratory findings include serum creatinine of 2.8 mg/dL and urea nitrogen of 30 mg/dL. A renal biopsy is performed and on microscopic examination shows focal necrosis in glomeruli with glomerular basement membrane breaks and crescent formation. No immune deposits are identified with immunofluorescence. Which of the following autoantibodies is most likely detectable in her serum?

Onion skin lesions, in the muscular layer of arteriole, are seen in which of the following conditions?

Renal angiomyolipoma is associated with which of the following conditions?

HIV infection is most commonly associated with which type of glomerulonephritis?

Nephrocalcinosis is seen in which of the following conditions?

A patient with clinical features of Glomerulonephritis presents with granular staining on immunofluorescence. All of the following causes are associated with normal C3 levels except?

Which gene is commonly involved in mutations leading to renal cell carcinoma?

A 10-year-old child with a history of sore throat one week ago presents with sudden onset of hematuria, generalized edema, and hypertension. Laboratory findings reveal proteinuria, red blood cell casts in the urine, deranged renal function tests, and low serum complement C3 levels. What is the most likely histological finding if a kidney biopsy is performed?

What is the most common predisposing factor for chronic pyelonephritis?

Which of the following statements is FALSE regarding Goodpasture's disease?