Osteoarthritis: Pathophysiology — MCQs

Osteoarthritis is associated with all of the following except -

What is the primary action of metalloproteinases in the extracellular matrix?

Osteoarthritis not seen in ?

During performing a total hip replacement, the surgeon found destruction of the articular cartilage and multiple wedge-shaped subchondral depressions. What is this called?

Which of the following joints are commonly affected in osteoarthritis? I. First metatarsophalangeal joint II. Proximal interphalangeal joint III. Ankle joint IV. 5th and 6th cervical vertebrae joint Select the correct answer using the code given below :

Primary osteoarthritis affects all except:

Osteoarthritis is typically not seen in which of the following joints?

In patients with osteoarthritis of the knee joint, atrophy occurs most commonly in which muscle?

What is the deformity most commonly seen in primary osteoarthritis of the knee joint?

A 74-year-old woman presents with a months-long history of pain in her right hand and lower back, which is worsening and interfering with her daily activities. The pain increases as the day progresses. She denies any history of trauma and is otherwise healthy. Over-the-counter acetaminophen usually provides relief. On examination, there is soft tissue swelling and tenderness of her second and third distal interphalangeal joints in the right hand, and she experiences pain in her lower back upon forward flexion. There is no erythema or joint effusion in any other joints. What is the most likely explanation for the joint pain in osteoarthritis?