Autoimmune Skin Diseases — MCQs

A 77-year-old Asian woman reports developing skin abscesses and oral ulcers following minor trauma. What is the most likely diagnosis?

A 30-year-old pregnant woman presents with painful oral ulcers. Physical examination demonstrates widespread erosions of her mucous membranes and a friable mucosa, but no well-defined aphthous ulcers. Biopsy of perilesional mucosa demonstrates acantholysis, and direct immunofluorescence demonstrates an intraepidermal band of IgG and C3. Which of the following is the most likely diagnosis?

A patient presents with ill-defined, irregularly shaped, painful gingival erosions of short duration. A few months later, skin lesions were also noticed. On histopathological examination, Tzanck cells were found. What is the probable diagnosis?

What is the treatment of choice for Sweet's syndrome?

A patient has oral ulcer and skin bullae, which are slow to heal. The lesion is:

An 82-year-old man presents with a 1 and a half-week history of severe pruritus and eczema. His past medical history includes atopic dermatitis, thyroid disease, and multiple sclerosis. On physical examination, he has dozens of 1-2 cm tense bullae and several erosions over his upper and lower extremities. His oral mucosa is not involved. Nikolsky sign is negative. A skin biopsy is taken and anti-BP 180 is detected in his blood. A potent topical steroid is prescribed. What is the most likely diagnosis?

Intraepidermal blisters are seen in which of the following conditions?

Which bullous disease is characterized by the formation of autoantibodies against antigens of epidermal intercellular junctions?

Which of the following is NOT typically seen in dermatomyositis?

A 27-year-old G1P0 female at 36 weeks gestation presents with a 3-day history of abrupt onset of extremely pruritic and urticarial papules and blisters on the abdomen and trunk, which has worsened to interfere with her everyday life. What is the most likely diagnosis?