miRNA and RNA Interference — MCQs

Which discovery in gene regulation was awarded the Nobel Prize in Physiology or Medicine in 2006?

During eukaryotic protein synthesis, phosphorylation of which of the following is enhanced by insulin?

Which of the following statements best describes the mechanism of action of insulin on target cells?

Which of the following statements about gene therapy is false?

What is the gene fusion associated with Ewing's sarcoma?

Which of the following is a primarily RNA based technique?

What is the primary function of the sigma subunit of prokaryotic RNA polymerase?

Which type of RNA is primarily involved in gene silencing?

A research team is developing a gene therapy approach using CRISPR-Cas9 to correct a point mutation causing sickle cell disease. They must decide between two strategies: (A) correcting the mutation in hematopoietic stem cells ex vivo, or (B) in vivo correction in bone marrow. Considering molecular physiology principles, what is the most significant advantage of strategy A over strategy B?

How does alternative splicing contribute to protein diversity in humans despite having approximately 20,000 genes?