FMGE 2018 Practice Questions

Q: Tibial and common peroneal nerves supply which of the following muscles?

Biceps femoris. **Biceps femoris** - The **long head** of the biceps femoris is supplied by the **tibial nerve**. - The **short head** of the biceps femoris is supplied by the **common peroneal nerve**. *Gracilis* - The gracilis muscle is solely innervated by the **obturator nerve**. - It participates in **hip adduction** and **knee flexion**, but its innervation is distinct. *Adductor longus* - The adductor longus muscle is innervated exclusively by the **obturator nerve**. - Its primary function is **adduction of the thigh**. *Adductor magnus* - The adductor magnus has a dual innervation, but not by the tibial and common peroneal nerves. - Its **adductor part** is innervated by the **obturator nerve**, while its **hamstring part** is supplied by the **tibial nerve**.

Q: Which part of thalamus is related to motor control?

Ventrolateral thalamus. ***Ventrolateral thalamus*** - The **ventrolateral (VL) nucleus** of the thalamus is a key relay station for **motor control**, receiving input from the **basal ganglia** and **cerebellum** and projecting to the motor cortex [1]. - It plays a crucial role in the planning, initiation, and coordination of **voluntary movements**. *Ventral posteromedial* - The **ventral posteromedial (VPM) nucleus** is involved in processing **somatosensory information** from the face and taste sensations. - It does not primarily contribute to motor control pathways. *Ventral posterolateral* - The **ventral posterolateral (VPL) nucleus** relays **somatosensory information** from the body (limbs and trunk) to the primary somatosensory cortex. - Its main function is sensory perception, not motor control. *Lateral geniculate nucleus* - The **lateral geniculate nucleus (LGN)** is exclusively involved in the **visual pathway**, receiving input from the retina and projecting to the primary visual cortex. - It has no direct role in motor control.

Q: Atherosclerosis is associated with:

Homocysteine. ***Homocysteine*** - Elevated plasma levels of **homocysteine**, known as hyperhomocysteinemia, are an independent **risk factor for atherosclerosis** and cardiovascular disease. - While the precise mechanism is complex, homocysteine is thought to promote endothelial damage, oxidative stress, and lipid peroxidation, contributing to **plaque formation**. *Histidine* - **Histidine** is an essential amino acid involved in various metabolic processes, including the synthesis of **histamine** and carnosine. - It is not directly associated with the pathogenesis or risk factors for atherosclerosis. *Lysine* - **Lysine** is an essential amino acid important for **protein synthesis** and many bodily functions. - There is no established direct link between lysine levels and the development or progression of atherosclerosis. *Leucine* - **Leucine** is a branched-chain amino acid (BCAA) crucial for **muscle protein synthesis** and energy metabolism. - While some studies hint at associations between BCAAs and metabolic health, leucine itself is not a known direct risk factor or etiologic agent for atherosclerosis.

Q: Young's operation is done for:

Atrophic rhinitis. ***Atrophic rhinitis*** - **Young's operation** is a surgical procedure specifically designed to treat **atrophic rhinitis**. - The goal of the surgery is to narrow the nasal passages by creating a **synechia** (adhesion) to reduce airflow and improve the humidification and temperature of inspired air. *Allergic rhinitis* - Allergic rhinitis is primarily managed with **medical therapy**, including antihistamines, nasal corticosteroids, and allergen avoidance. - Surgical intervention, if considered, typically involves procedures like turbinate reduction, not Young's operation, and is less common for this condition. *Vasomotor rhinitis* - Vasomotor rhinitis is a **non-allergic, non-infectious condition** characterized by fluctuating nasal congestion and rhinorrhea, often triggered by irritants or temperature changes. - Treatment usually involves **medical management** with anticholinergics or nasal corticosteroids, and sometimes turbinate reduction, but not Young's operation. *Antrochoanal polyp* - An antrochoanal polyp is a benign growth originating in the **maxillary sinus** and extending into the choana. - The primary treatment is **surgical removal**, typically via endoscopic sinus surgery, which is distinct from Young's operation.

Q: A 15 years old Male presented with history of fever since 2 days, unable to swallow the food with muffled voice. On examination it is noted right tonsil is shifted to midline. What is the diagnosis:

Quincy. ***Quincy (Peritonsillar abscess)*** - This patient's presentation with **fever**, **dysphagia**, **muffled voice** (hot potato voice), and **tonsil shifted to the midline** is classic for a **peritonsillar abscess (Quincy)**. - The affected tonsil is pushed **medially toward the midline** by the collection of pus between the tonsillar capsule and the superior constrictor muscle. - The uvula is typically deviated to the **contralateral side**, and patients often have **trismus** and difficulty opening the mouth. - This is the **most common deep neck space infection** and typically follows acute tonsillitis. *Parapharyngeal abscess* - A **parapharyngeal abscess** would present with **severe trismus**, **neck swelling**, **torticollis**, and **bulging of the lateral pharyngeal wall**. - While it can push the tonsil medially, it more characteristically causes **anterolateral displacement** of the entire pharyngeal wall rather than isolated tonsillar displacement. - Patients typically have more pronounced **systemic toxicity** and **neck involvement** than seen with peritonsillar abscess. *Acute tonsillitis* - **Acute tonsillitis** presents with **bilateral tonsillar enlargement**, exudates, and pharyngeal erythema. - It does not cause **displacement of the tonsil to the midline** or significant **muffled voice**. - While fever and dysphagia are present, the physical examination finding of tonsillar shift indicates a suppurative complication (abscess formation). *Acute retropharyngeal abscess* - An **acute retropharyngeal abscess** occurs in the retropharyngeal space behind the posterior pharyngeal wall. - It presents with **neck stiffness**, **stridor**, **drooling**, **bulging of the posterior pharyngeal wall**, and **reluctance to extend the neck**. - It would **not cause visible displacement of the tonsil to the midline** as the abscess is in a different anatomical space. - More common in **young children** (under 5 years) than adolescents.

Q: Which of the following is not a component of Jones criteria for diagnosing acute rheumatic fever?

Erythema nodosum. ***Erythema nodosum*** - **Erythema nodosum** is a delayed hypersensitivity reaction characterized by tender, red nodules, typically on the shins, but it is **not a major or minor criterion** in the Jones criteria for acute rheumatic fever. - While it can be associated with various inflammatory conditions, including streptococcal infections, its presence alone does not establish a diagnosis of **acute rheumatic fever (ARF)**. *Sydenham chorea* - **Sydenham chorea** is a major manifestation of ARF, characterized by involuntary, purposeless movements, and it is a key diagnostic criterion [1]. - It results from central nervous system involvement due to **autoimmune reaction** against basal ganglia. *Pancarditis* - **Pancarditis** (inflammation of all layers of the heart) is a major criterion for ARF, often leading to valvular damage, especially mitral stenosis [1]. - It can manifest as **pericarditis**, **myocarditis**, or **endocarditis** [1]. *Migratory polyarthritis* - **Migratory polyarthritis** is a major criterion for ARF, involving painful inflammation that moves from one joint to another. - It typically affects large joints such as the **knees, ankles, elbows, and wrists**.

Q: Cornea derives its nutrition chiefly from:

Aqueous humour. ***Aqueous humour*** - The cornea is **avascular**, meaning it lacks its own blood vessels, and thus relies on the **aqueous humor** for metabolic support. - The aqueous humor, located in the anterior chamber, provides **glucose, amino acids, and oxygen** to the posterior surface of the cornea. *Corneal vessels* - The **cornea is avascular** under normal physiological conditions; the presence of corneal vessels (neovascularization) is typically a sign of pathology. - This avascularity is crucial for maintaining corneal transparency and optimal vision. *Perilimbal vessels* - Perilimbal vessels (at the limbus, the junction between cornea and sclera) primarily supply the **periphery of the cornea** and the limbal stem cell niche, not the entire cornea's main nutritional needs. - While they contribute some oxygen and nutrients, the **aqueous humor** is the predominant source for the central and posterior cornea. *Mucous layer* - The mucous layer, part of the tear film, primarily functions in **lubrication and adhesion** of the tear film to the corneal surface. - While it contains some dissolved oxygen from the atmosphere to supply the anterior cornea, its role in nutrient supply (glucose, amino acids) is **minimal** compared to the aqueous humor.

Q: Sarcoidosis is associated with

Anterior uveitis. ***Anterior uveitis*** - **Anterior uveitis**, particularly chronic granulomatous anterior uveitis, is the most common ocular manifestation of **sarcoidosis**. - It results from **non-caseating granulomas** affecting the iris and ciliary body. - Sarcoidosis can also cause intermediate uveitis, posterior uveitis, and panuveitis, but anterior uveitis is most frequently seen. - Characteristic findings include mutton-fat keratic precipitates and iris nodules (Koeppe and Busacca nodules). *Keratitis* - **Keratitis** (inflammation of the cornea) is less commonly associated with sarcoidosis compared to uveitis. - While ocular sarcoidosis can rarely cause interstitial keratitis or band keratopathy, direct corneal inflammation is not a hallmark feature. *Cataract* - **Cataracts** are not directly caused by sarcoidosis itself, but can be a complication of chronic uveitis or prolonged corticosteroid treatment. - The disease process of sarcoidosis does not primarily involve cataract formation. *Ectopia lentis* - **Ectopia lentis** (lens dislocation) is a rare condition usually associated with genetic disorders like **Marfan syndrome** or homocystinuria. - It is not a recognized ocular manifestation of sarcoidosis.

Q: Blount Disease is involvement of

Proximal tibia. ***Proximal tibia*** - Blount disease, also known as **tibia vara**, is a growth disorder affecting the **tibia** (shin bone) in children. - It specifically involves the **medial physis of the proximal tibia**, leading to abnormal growth in this area and resulting in a **bow-legged** deformity. *Distal femur* - Malformations or growth disturbances of the **distal femur** are typically associated with conditions like genu valgum (**knock-knees**) or other angular deformities originating higher up in the leg. - Blount disease's primary pathology does not originate from the distal femur. *Distal tibia* - Conditions affecting the **distal tibia** can lead to ankle deformities or foot problems. - Blount disease is distinctly a problem of the knee region, not the ankle. *Proximal femur* - Problems in the **proximal femur** are commonly associated with conditions like Legg-Calvé-Perthes disease or developmental dysplasia of the hip. - While these can also cause gait abnormalities, Blount disease's characteristic bowing deformity originates from the tibia.

Q: Which of the following hormones regulates blood levels of 1,25-OH-cholecalciferol positively?

Parathormone. ***Parathormone*** - **Parathormone (PTH)** directly stimulates the **renal 1-alpha-hydroxylase** enzyme, which converts 25-hydroxycholecalciferol to its active form, **1,25-dihydroxycholecalciferol (calcitriol)**. - This activation is crucial for increasing **calcium absorption** from the gut and maintaining calcium homeostasis. *Thyroxine* - **Thyroxine** (thyroid hormone) primarily regulates **metabolism**, growth, and development. - It does not have a direct positive regulatory effect on the synthesis or blood levels of **1,25-OH-cholecalciferol**. *Calcitonin* - **Calcitonin** is a hormone that **lowers blood calcium levels** by inhibiting osteoclast activity and decreasing renal calcium reabsorption. - It does not positively regulate the production of **1,25-OH-cholecalciferol**; in fact, its actions are generally antagonistic to those influenced by active vitamin D. *Insulin* - **Insulin** is a key hormone in **glucose metabolism**, facilitating glucose uptake by cells and promoting glycogen synthesis. - It plays no direct role in the regulation or synthesis of **1,25-OH-cholecalciferol**.

Question 1

Tibial and common peroneal nerves supply which of the following muscles?

Accepted Answer

Biceps femoris

Answer

Gracilis

Answer

Adductor longus

Answer

Adductor magnus

Question 2

Which part of thalamus is related to motor control?

Accepted Answer

Ventrolateral thalamus

Answer

Ventral posteromedial

Answer

Ventral posterolateral

Answer

Lateral geniculate nucleus

Question 3

Atherosclerosis is associated with:

Accepted Answer

Homocysteine

Answer

Histidine

Answer

Lysine

Answer

Leucine

Question 4

Young's operation is done for:

Accepted Answer

Atrophic rhinitis

Answer

Allergic rhinitis

Answer

Vasomotor rhinitis

Answer

Antrochoanal polyp

Question 5

A 15 years old Male presented with history of fever since 2 days, unable to swallow the food with muffled voice. On examination it is noted right tonsil is shifted to midline. What is the diagnosis:

Accepted Answer

Quincy

Answer

Acute tonsillitis

Answer

Parapharyngeal abscess

Answer

Acute retropharyngeal abscess

Question 6

Which of the following is not a component of Jones criteria for diagnosing acute rheumatic fever?

Accepted Answer

Erythema nodosum

Answer

Sydenham chorea

Answer

Pancarditis

Answer

Migratory polyarthritis

Question 7

Cornea derives its nutrition chiefly from:

Accepted Answer

Aqueous humour

Answer

Corneal vessels

Answer

Perilimbal vessels

Answer

Mucous layer

Question 8

Sarcoidosis is associated with

Accepted Answer

Anterior uveitis

Answer

Keratitis

Answer

Cataract

Answer

Ectopia lentis

Question 9

Blount Disease is involvement of

Accepted Answer

Proximal tibia

Answer

Distal femur

Answer

Distal tibia

Answer

Proximal femur

Question 10

Which of the following hormones regulates blood levels of 1,25-OH-cholecalciferol positively?

Accepted Answer

Parathormone

Answer

Thyroxine

Answer

Calcitonin

Answer

Insulin

FMGE 2018

Anatomy

Biochemistry

ENT

Internal Medicine

Ophthalmology

Orthopaedics

Physiology