Antipsychotic mechanisms of action — Flashcards

Flashcard 1: The nigrostriatal pathway is significantly affected by movement disorders and _____ drugs

Answer: antipsychotic

Flashcard 2: What features of extrapyramidal symptoms may be treated with beta-blockers, benzodiazepines, and benztropine?_____

Answer: Akathisia

Flashcard 3: What features of extrapyramidal symptoms may be treated with benztropine and diphenhydramine?_____

Answer: Acute Dystonia

Flashcard 4: In addition to schizophrenia, typical antipsychotics are used to treat _____ in many conditions (e.g. bipolar disorder, delirium)

Answer: psychosis

Flashcard 5: Broca's aphasia

Answer: damage to inferior frontal gyrus of dominant frontal lobe

Extra: nonfluent speech, intact comprehensionmnemonic: Broca's Broken Boca

Flashcard 6: Wernicke's aphasia

Answer:

Extra: fluent but nonsensical speech, impaired comprehensionmnemonic: Wernicke's Wordy Widdershins (widdershins is nonsense in this context)superior temporal gyrus of dominant temporal lobe

Flashcard 7: global aphasia

Answer: damage to both Broca's and Wernicke's areas (dominant frontal and temporal lobes)

Extra: nonfluent speech, impaired comprehension

Flashcard 8: olfaction

Answer: limbic system

Flashcard 9: GABA

Answer: nucleus accumbens

Flashcard 10: Which dopamine receptor is associated with the direct pathway of the basal ganglia?

Answer: D1 mnemonic: D1rect