Lewy body dementia — Flashcards

Flashcard 1: The nigrostriatal pathway is significantly affected by movement disorders and _____ drugs

Answer: antipsychotic

Flashcard 2: When diagnosing neurodegenerative disorders, you must first rule out _____ as a cause of the presenting dementia

Answer: depression (psych disorder)

Flashcard 3: Early-onset dementia with Parkinsonian features is suggestive of _____ dementia

Answer: Lewy body

Flashcard 4: mammillary bodies

Answer: confusion, ophthalmoplegia, ataxia, confabulation, personality change, permanent anterograde and retrograde amnesia

Flashcard 5: frontal lobe

Answer: disinhibition; deficits in concentration, orientation, judgment; reemergence of primitive reflexes

Flashcard 6: conduction aphasia

Answer: damage to arcuate fasciculus of dominant hemisphere

Extra: fluent speech, intact comprehension, impaired repetition

Flashcard 7: aphasia

Answer: speech deficit due to high-order processing problem

Flashcard 8: long-term memory

Answer: limbic system

Flashcard 9: Alzheimer's disease

Answer:

Extra: decreased: ACh

Flashcard 10: Wernicke-Korsakoff syndrome

Answer: vitamin B1 (thiamine) deficiency, possibly precipitated by glucose administration concurrent without thiamine administration

Extra: damage to medial dorsal nucleus of thalamus and mammillary bodiesconfusion, opthalmoplegia, ataxia, confabulation, personality change, permanent anterograde and retrograde amnesiadamage to medial dorsal nucleus of thalamus and mammillary bodiesvitamin A will halt progression, but won't restore most changesalcoholism (malnutrition and malabsorption)