Potassium balance and regulation — Flashcards

Flashcard 1: Aldosterone upregulates the _____ pump on the basolateral membrane of the principal cells

Answer: Na+-K+ ATPase

Flashcard 2: What is the effect of insulin on Na+-K+-ATPase activity?_____

Answer: Increased (thus causing increased K+ uptake into cells)

Flashcard 3: Aldosterone upregulates _____ channels on the apical membranes of the principal cells, increasing K+ excretion

Answer: K+

Flashcard 4: Aldosterone upregulates _____ on the apical membrane of the principal cells, increasing Na+ reabsorption

Answer: ENaCs

Flashcard 5: In principal cells, increased ENaC activity (due to aldosterone) causes increased lumen _____ (charge)

Answer: negativity

Flashcard 6: The outer rim of the islet of Langerhans contains mostly _____ cells

Answer: alpha

Extra:   https://onlinemeded.org/spa/surgery-general/pancreas/acquire?ref=anki Atlas: 

Flashcard 7: The [TF/P]glucose and [TF/P]AA ratios _____ over the course of the PCT

Answer: decrease

Extra:   https://onlinemeded.org/spa/renal?ref=anki 

Flashcard 8: The corticopapillary osmotic gradient is established, in part, by _____ multiplication

Answer: countercurrent

Extra:  https://onlinemeded.org/spa/nephrology?ref=anki 

Flashcard 9: The Na+ reabsorption mechanism of the thick ascending limb is _____-dependent (increased Na+ delivery causes increased reabsorption)

Answer: load

Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/nephrology/videos/nephron-transporters?index=4] https://onlinemeded.org/spa/renal?ref=anki 

Flashcard 10: Glomerulotubular balance describes a balance between filtration in the _____ and reabsorption in the _____

Answer: glomerulus

Extra:   https://onlinemeded.org/spa/renal?ref=anki