Diuretic mechanisms of action — Flashcards

Flashcard 1: Thiazide diuretics increase Ca2+ _____ (excretion or reabsorption)

Answer: reabsorption

Flashcard 2: Aldosterone upregulates _____ channels on the apical membranes of the principal cells, increasing K+ excretion

Answer: K+

Flashcard 3: Proximal renal tubular acidosis is associated with _____-kalemia

Answer: hypo

Flashcard 4: Where in the nephron do acetazolamide and mannitol primarily exert their effects? _____

Answer: Proximal convoluted tubule

Flashcard 5: Following the thin descending limb, glomerular filtrate enters the _____

Answer: thin ascending limb (loop of Henle)

Flashcard 6: The outer rim of the islet of Langerhans contains mostly _____ cells

Answer: alpha

Extra:   https://onlinemeded.org/spa/surgery-general/pancreas/acquire?ref=anki Atlas: 

Flashcard 7: The [TF/P]glucose and [TF/P]AA ratios _____ over the course of the PCT

Answer: decrease

Extra:   https://onlinemeded.org/spa/renal?ref=anki 

Flashcard 8: The corticopapillary osmotic gradient is established, in part, by _____ multiplication

Answer: countercurrent

Extra:  https://onlinemeded.org/spa/nephrology?ref=anki 

Flashcard 9: The Na+ reabsorption mechanism of the thick ascending limb is _____-dependent (increased Na+ delivery causes increased reabsorption)

Answer: load

Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/nephrology/videos/nephron-transporters?index=4] https://onlinemeded.org/spa/renal?ref=anki 

Flashcard 10: Glomerulotubular balance describes a balance between filtration in the _____ and reabsorption in the _____

Answer: glomerulus

Extra:   https://onlinemeded.org/spa/renal?ref=anki