Which one of the following drugs is a cytochrome p450 inducer?_____
#2
Which drug elimination is characterized by a constant fraction of drug eliminated per unit time?_____
#3
Benzodiazepines are metabolized by the _____
#4
Phase _____ drug metabolism usually yields slightly polar, water-soluble metabolites (often still active)
#5
What phase of drug metabolism includes reduction, oxidation, and hydrolysis? _____
#6
Rectal and sublingual administration have such high bioavailability because drugs will _____
#7
Acute alcohol use leads to _____ of CYP-450
First-pass metabolism US Medical PG Flashcards - Medical Study Cards
Master First-pass metabolism with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
First-pass metabolism Flashcard Deck - 7 Cards
Flashcard 1: Which one of the following drugs is a cytochrome p450 inducer?_____
Answer: Rifampin
Flashcard 2: Which drug elimination is characterized by a constant fraction of drug eliminated per unit time?_____
Answer: First-order elimination
Flashcard 3: Benzodiazepines are metabolized by the _____
Answer: liver
Flashcard 4: Phase _____ drug metabolism usually yields slightly polar, water-soluble metabolites (often still active)
Answer: I
Flashcard 5: What phase of drug metabolism includes reduction, oxidation, and hydrolysis? _____
Answer: Phase I
Flashcard 6: Rectal and sublingual administration have such high bioavailability because drugs will _____
Answer: bypass portal circulation*
Flashcard 7: Acute alcohol use leads to _____ of CYP-450
Answer: inhibition
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First-pass metabolism Flashcards for USMLE
Study 7 flashcards on First-pass metabolism for USMLE Pharmacology. These active recall cards cover the key concepts, clinical associations, and high-yield facts from this chapter of Pharmacokinetics (ADME principles). Each card is designed to test your understanding rather than just recognition, building stronger and more durable memories for exam day.
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There are 7 flashcards for First-pass metabolism, covering the key concepts, clinical correlations, and high-yield facts from this chapter of Pharmacokinetics (ADME principles).
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Read through each prompt and try to answer before revealing the back of the card. This active recall approach builds stronger memories than passive reading. Combine flashcards with the study notes and MCQ practice for the best results.
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