Cholinergic/Adrenergic drugs — Flashcards

Flashcard 311: What drug class do venlafaxine and desvenlafaxine belong to?_____

Answer: SNRIs

Flashcard 312: What is a lethal complication of cholinesterase inhibitor poisoning if untreated?_____

Answer: Respiratory failure

Flashcard 313: What effect do alpha-2 agonists have on sympathetic tone?

Answer: Decreased (sympatholytic)

Flashcard 314: What drug is used for chronic pain in tension headaches? _____

Answer: Amitriptyline

Flashcard 315: _____ are glaucoma drugs that are associated with ocular hyperemia, foreign body sensation, and ocular pruritis

Answer: a2-agonists

Flashcard 316: Glycopyrrolate is a(n) _____ antagonist

Answer: Muscarinic

Extra: Glycopyrrolate is a **non-selective** muscarinic antagonist. It is a **quaternary ammonium** compound, meaning it does not cross the blood-brain barrier and has minimal CNS side effects (unlike atropine). It is often used to reduce secretions (antisialogogue) and to prevent bradycardia during the reversal of neuromuscular blockade.

Flashcard 317: Phenylephrine causes reflex _____ (HR)

Answer: bradycardia

Flashcard 318: Is phentolamine (alpha-blocker) reversible or irreversible?

Answer: Reversible

Flashcard 319: What drug class does atropine belong to? _____

Answer: Anti-muscarinics

Flashcard 320: What sympathomimetic catecholamine is used to treat septic shock? _____

Answer: Norepinephrine