Cholinergic/Adrenergic drugs — Flashcards

Flashcard 291: Long-acting beta-2 agonists are used for _____ in moderate or severe persistent asthma

Answer: prophylaxis

Flashcard 292: Adverse effects of paroxetine include anti-_____ effects, sleep disturbances (abnormal dreams), and sexual dysfunction

Answer: cholinergic

Extra: Paroxetine is unique among SSRIs for having significant anticholinergic activity. While most SSRIs primarily cause GI upset (nausea), sexual dysfunction, and sleep disturbances, paroxetine's side effect profile also includes dry mouth and constipation due to its muscarinic antagonism. Note: Vortioxetine (the drug previously listed on this card) is an atypical antidepressant that lacks significant anticholinergic effects and is most commonly associated with nausea.

Flashcard 293: Glycopyrrolate is an _____ receptor antagonist that is used to reduce activity of glands

Answer: M3 (specific receptor)

Flashcard 294: Acetylcholinesterase inhibitors may be used to treat urinary _____

Answer: retention

Flashcard 295: The _____ muscarinic receptor is found in glands, the bladder, and smooth muscle

Answer: M3

Flashcard 296: Cholinomimetic drugs mimic the neurotransmitter _____

Answer: acetylcholine

Flashcard 297: Phenylephrine may be used as a _____ for ocular procedures

Answer: mydriatic

Flashcard 298: Is bupropion use associated with sexual dysfunction? _____

Answer: No

Flashcard 299: Examples of the beers criteria include drugs that increase the risk of anti_____ activity (antihistamines, GI antispasmodics)

Answer: cholinergic

Flashcard 300: What G-protein is the M1 muscarinic receptor coupled to? _____

Answer: Gq