Phosphodiesterase inhibitors — Flashcards

Flashcard 1: In addition to erectile dysfunction, sildenafil may also be used to treat _____

Answer: pulmonary hypertension

Flashcard 2: PDE-5 inhibitors (e.g. sildenafil, tadalafil) are indicated for _____ hypertension

Answer: pulmonary

Flashcard 3: Milrinone and inamrinone are _____ inhibitors used in the treatment of acute heart failure

Answer: PDE-3

Flashcard 4: The following drugs are good for Hypertension and Heart Failure as they help prevent _____ACE inhibitors, Beta-blockers (compensated HF), and Aldosterone Antagonists

Answer: cardiac remodeling

Flashcard 5: What drug class do vardenafil, tadalafil, and sildenafil belong to?_____

Answer: PDE-5 inhibitors

Flashcard 6: vardenafil

Answer: PDE5 inhibitor

Extra: erectile dysfunctionpatients taking nitrates (lethal hypotension)inhbit phosphodiesterase 5, resulting in increased cGMP and smooth muscle relaxation in corpus cavernosumheadache, flushing, impaired blue-green color vision, hypotension, dyspepsia

Flashcard 7: sildenafil

Answer: PDE5 inhibitor

Extra: erectile dysfunctionpatients taking nitrates (lethal hypotension)inhbit phosphodiesterase 5, resulting in increased cGMP and smooth muscle relaxation in corpus cavernosumheadache, flushing, impaired blue-green color vision, hypotension, dyspepsia

Flashcard 8: aspirin

Answer:

Extra: increases permeability of the mitochondrial membrane (incomplete)inhibit oxidative phosphorylation

Flashcard 9: ouabain

Answer:

Extra: inhibits Na+-K+ ATPase by binding to K+ site

Flashcard 10: Ischemic priapism is treated with corporal aspiration, intracavernosal _____, or surgical decompression to prevent ischemia

Answer: phenylephrine

Extra:  https://onlinemeded.org?ref=anki