Autonomic/CV Drugs — Flashcards

Flashcard 2721: What is the effect of beta-blockers alone on myocardial O2 consumption?

Answer: Decreased

Extra: Beta-blockers decrease heart rate and contractility (which decreases myocardial $O_2$ consumption). \n\nNote: They can increase end-diastolic volume (EDV) and ejection time, which increases $O_2$ demand, but the overall net effect is a decrease in $MVO_2$.

Flashcard 2722: Class IA antiarrhythmics have a(n) _____ binding affinity for the Na+ channel

Answer: intermediate

Flashcard 2723: Cromolyn sodium is an asthma therapeutic that inhibits _____

Answer: mast cell degranulation

Flashcard 2724: Fat-soluble vitamin deficiencies may occur with _____ intake, which can be used to treat constipation

Answer: mineral oil

Flashcard 2725: Midodrine may exacerbate _____ hypertension

Answer: supine

Flashcard 2726: What drug class do mifepristone and ulipristal belong to?

Answer: Anti-progestins

Flashcard 2727: Non-dihydropyridine CCBs are useful for treating angina due to their ability to decrease _____ demand

Answer: myocardial oxygen

Flashcard 2728: What biliary tree complication may be caused by opiates? _____ or Sphincter of Oddi Spasm

Answer: Biliary colic

Flashcard 2729: Spironolactone may have anti-androgenic effects via direct antagonism of the _____ receptor

Answer: androgen

Flashcard 2730: What eye movement is associated with phencyclidine (PCP) intoxication? _____

Answer: Nystagmus