Autonomic/CV Drugs — Flashcards

Flashcard 2711: Inhibition of the SA node by non-dihydropyridine CCBs can cause _____

Answer: bradycardia

Flashcard 2712: Serum Sickness can be treated with pulsed _____ therapy

Answer: corticosteroid

Flashcard 2713: What biliary tree complication may be caused by opiates? _____ or Sphincter of Oddi Spasm

Answer: Biliary colic

Flashcard 2714: Opioid agonists (e.g. diphenoxylate, loperamide) treat diarrhea by activating _____ receptors in the GI tract

Answer: μ-opioid (mu)

Flashcard 2715: What is the effect of beta-blockers alone on myocardial O2 consumption?

Answer: Decreased

Extra: Beta-blockers decrease heart rate and contractility (which decreases myocardial $O_2$ consumption). \n\nNote: They can increase end-diastolic volume (EDV) and ejection time, which increases $O_2$ demand, but the overall net effect is a decrease in $MVO_2$.

Flashcard 2716: Non-dihydropyridine CCBs are useful for treating angina due to their ability to decrease _____ demand

Answer: myocardial oxygen

Flashcard 2717: _____ is a monoclonal IgG antibody against the GPIIb/IIIa receptor

Answer: Abciximab

Flashcard 2718: Prostaglandins decrease gastric acid secretion by decreasing levels of _____ (second messenger)

Answer: cAMP

Flashcard 2719: What are the first-line pharmacologic treatments (2) for social anxiety disorder? _____

Answer: SSRIs or venlafaxine

Flashcard 2720: What drug class do montelukast and zafirlukast belong to? _____

Answer: Leukotriene D4-receptor antagonists