Autonomic/CV Drugs — Flashcards

Flashcard 2671: One adverse effect associated with digoxin is _____ (HR)

Answer: bradycardia

Flashcard 2672: Triptans _____ release of vasoactive peptides

Answer: prevent

Flashcard 2673: _____ is used for prophylaxis and acute management of DVT

Answer: Unfractionated or LMW heparin

Flashcard 2674: Sunitinib and sorafenib treat cancer due to VEGFR overexpression, such as _____ carcinoma

Answer: renal cell

Flashcard 2675: Benzodiazepines _____ the action of GABAA (enhance or inhibit)

Answer: enhance

Flashcard 2676: Glucocorticoids are useful for _____ therapy (e.g. transplant rejection prevention, treatment of autoimmune disorders)

Answer: immunosuppressive

Flashcard 2677: Which anti-epileptic is most associated with DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms)? _____

Answer: Phenytoin

Flashcard 2678: Is mannitol associated with hypernatremia or hyponatremia as a possible adverse effect? _____

Answer: Both

Extra: Mannitol can cause both: 1. **Hyponatremia**: Initially, mannitol expands the extracellular fluid volume by pulling water out of cells, resulting in dilutional hyponatremia. 2. **Hypernatremia**: Subsequently, it leads to osmotic diuresis. Since water is lost in excess of sodium (free water clearance), this can lead to dehydration and hypernatremia.

Flashcard 2679: Carbamazepine exerts its effects by blocking _____ channels

Answer: Na+

Flashcard 2680: What 5-aminosalicylic preparations (2) are useful in the management of ulcerative colitis and Crohn disease? _____

Answer: Mesalamine and sulfasalazine