Autonomic/CV Drugs — Flashcards

Flashcard 2621: As part of the reversal of digoxin toxicity, _____ can be given to bind and neutralize digoxin.

Answer: Anti-digoxin Fab fragments

Flashcard 2622: Does administering HCO3 for tricyclic antidepressant toxicity accelerate drug metabolism?_____

Answer: No - only overcomes Na channel-blocking activity

Flashcard 2623: First Aid Pharmacology: Respiratory (Asthma) _____ are the first line therapy for chronic asthma

Answer: Inhaled corticosteroids

Flashcard 2624: Phenobarbital is an _____ of CYP-450

Answer: inducer

Flashcard 2625: Triptans inhibit _____ nerve activation

Answer: trigeminal

Flashcard 2626: What formula is used to calculate loading dose? _____

Answer: (Cp × Vd) / F

Extra: Cp = Target plasma concentration Vd = Volume of distribution F = Bioavailability Note: Loading dose depends on the **volume of distribution** (Vd). In contrast, maintenance dose depends on **clearance** (CL).

Flashcard 2627: What drug class is the most common cause of drug overdose death? _____

Answer: Opioids (e.g. heroin)

Flashcard 2628: What type of diabetes may be induced by glucocorticoid use? _____

Answer: Steroid diabetes

Flashcard 2629: First Aid Pharmacology: Neuro/Psych Vilazodone inhibits the pre-synaptic reuptake of _____

Answer: serotonin (5-HT)

Flashcard 2630: What effect do thrombolytics have on platelet count?_____

Answer: No effect