Antiarrhythmic classification and mechanisms — Flashcards

Flashcard 1: Cardiovascular (Antiarrhythmics) _____, a class III antiarrhythmic, has many neurologic side effects (e.g. tremor, ataxia, peripheral neuropathy, sleep disturbances)

Answer: Amiodarone

Flashcard 2: Class I_____ antiarrhythmics may be used to treat Wolff-Parkinson-White syndrome, a type of SVT

Answer: A

Flashcard 3: What effect do class I antiarrhythmics have on the action potentials of the SA and AV nodes?_____

Answer: No effect (only affects Na+-dependent action potentials)

Flashcard 4: Class I antiarrhythmics exert their actions by blocking _____ channels

Answer: Na+

Flashcard 5: Class IV antiarrhythmics are useful in the treatment of _____ fibrillation (and flutter)

Answer: atrial

Flashcard 6: What drug class does procainamide belong to? _____

Answer: Class IA antiarrhythmics

Flashcard 7: What class of anti-arrhythmic are -blockers? _____

Answer: Class II antiarrhythmics

Flashcard 8: What drug class do diltiazem and verapamil belong to? _____

Answer: Class IV antiarrhythmics (non-dihydropyridine Ca2+ channel blockers)

Flashcard 9: Metoprolol, propranolol, and esmolol are all examples of class _____ antiarrhythmics

Answer: II

Flashcard 10: vardenafil

Answer: PDE5 inhibitor

Extra: erectile dysfunctionpatients taking nitrates (lethal hypotension)inhbit phosphodiesterase 5, resulting in increased cGMP and smooth muscle relaxation in corpus cavernosumheadache, flushing, impaired blue-green color vision, hypotension, dyspepsia