Antivirals — Flashcards

Flashcard 251: What type of vaccine is the varicella vaccine? _____

Answer: Live attenuated

Flashcard 252: Which type of HAART drug is lamivudine (3TC)?_____

Answer: NRTI

Flashcard 253: Do NNRTIs compete with nucleotides for binding to reverse transcriptase?_____

Answer: No

Flashcard 254: What type of vaccine is the preferred Zoster vaccine (Shingrix)?

Answer: Recombinant subunit vaccine

Extra: Shingrix (Recombinant Zoster Vaccine) is the preferred vaccine for the prevention of herpes zoster (shingles). The Varicella (chickenpox) vaccine and the older Zoster vaccine (Zostavax) are live-attenuated vaccines. Shingrix is preferred due to higher efficacy and its non-live nature.

Flashcard 255: Which NRTI is associated with dose-dependent pancreatitis?_____

Answer: Didanosine

Flashcard 256: NRTIs lack a 3 hydroxyl group, causing strand termination when binding to _____

Answer: HIV reverse transcriptase

Flashcard 257: Treatment for CMV includes _____, Valganciclovir or Foscarnet/cidofovir

Answer: Ganciclovir

Flashcard 258: Which NRTI is associated with anemia and granulocytopenia?_____

Answer: Zidovudine

Flashcard 259: _____ is the prodrug form of Ganciclovir that has better oral bioavailability.

Answer: Valganciclovir

Flashcard 260: Which class of HAART drugs compete with nucleotides for binding to HIV reverse transcriptase?_____

Answer: NRTIs