Direct renin inhibitors — Flashcards

Flashcard 1: What effect do ACE inhibitors have on levels of angiotensin II? _____

Answer: Decreased AT II

Flashcard 2: What effect does aliskiren have on GFR? _____

Answer: Decreased GFR

Flashcard 3: ACE inhibitors can cause an _____ in creatinine levels within the first few days of starting treatment

Answer: elevation

Flashcard 4: First Aid Pharmacology: Cardiovascular/RenalACE inhibitors may cause angioedema due to increased _____

Answer: bradykinin

Flashcard 5: What is the primary clinical use for aliskiren? _____

Answer: Treatment of hypertension

Flashcard 6: What effect do ACE inhibitors have on bradykinin activity? _____

Answer: Increased

Flashcard 7: ACE inhibitors

Answer: renal damage

Flashcard 8: What is the mechanism of action of minoxidil? _____

Answer: Direct arteriolar vasodilator

Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/cardiology/videos/hypertension?index=12] https://onlinemeded.org?ref=anki 

Flashcard 9: _____-dilators (e.g. hydralazine) cause decreased after-load

Answer: Vaso

Extra:  Watch associated Bootcamp video [https://app.bootcamp.com/med-school/cardiology/videos/pressure-volume-loops?index=4] https://onlinemeded.org/spa/cardiology/heart-failure/acquire?ref=anki 

Flashcard 10: _____ channel blockers are useful for treating hypertension

Answer: Ca2+

Extra:   Sketchy Pharmacology: Cardiovascular Watch Calcium channel blockers [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-cardiovascular-renal/videos/medical-pharmacology-cardiovascular-and-renal-antihypertensives-calcium-channel-blockers?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/cardiology/videos/vasodilation-and-vasoconstriction?index=8] https://onlinemeded.org/spa/cardiac?ref=anki