Antifungals US Medical PG Flashcards - Medical Study Cards
Master Antifungals with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antifungals Flashcard Deck - 10 Cards
Flashcard 91: Angioinvasive aspergillosis is treated with _____
Answer: voriconazole
Extra: Voriconazole is the first-line treatment for invasive aspergillosis. Amphotericin B is an alternative treatment.
Flashcard 92: Amphotericin B related renal toxicity results in _____ due to decreased erythropoietin production
Answer: anemia
Extra:
Watch Amphotericin, flucytosine [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-amphotericin-flucytosine?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 93: Polyenes disrupt cell membrane stability by binding _____
Answer: ergosterol
Extra: Polyenes (e.g., amphotericin B, nystatin) bind to ergosterol in the fungal cell membrane, forming pores that cause leakage of electrolytes (especially potassium) and cell death.
Flashcard 94: Tinea capitis in children is treated with _____ or _____
Answer: oral griseofulvin
Extra:
Watch Griseofulvin, Terbinafine, Echinocandins [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-griseofulvin-terbinafine-echinocandins?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/dermatology/superficial-skin-infections/acquire?ref=anki
Flashcard 95: Can Nystatin be given for systemic fungal infections?
_____
Answer: No
Extra:
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 96: Which antifungal can cause a disulfiram-like reaction?
_____
Answer: Griseofulvin
Extra:
Watch Griseofulvin, Terbinafine, Echinocandins [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-griseofulvin-terbinafine-echinocandins?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 97: What is the treatment of choice for Naegleria fowleri?
_____
Answer: Amphotericin B
Extra:
Watch Naegleria fowleri [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-parasites/videos/medical-microbiology-parasites-protozoa-of-the-cns-naegleria-fowleri?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antifungals/acquire?ref=anki
Flashcard 98: Echinocandins are primarily metabolized via the _____
Answer: liver
Extra:
Watch Griseofulvin, Terbinafine, Echinocandins [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-griseofulvin-terbinafine-echinocandins?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 99: Griseofulvin is a cytochrome p450 _____
Answer: inducer
Extra:
https://onlinemeded.org/spa/pediatrics/seizures/acquire?ref=anki
Flashcard 100: _____ inhibits fungal nucleic acid synthesis by inhibiting the enzyme thymidylate synthase.
Answer: Flucytosine
Extra: Used for systemic fungal infections (e.g., Cryptococcus meningitis) in combination with amphotericin B. Side effects include bone marrow suppression.
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