Antibiotics — Flashcards

Flashcard 681: In patients with streptococcal infections who are allergic to penicillin, they should be given what class of antibiotics instead?_____

Answer: Macrolides

Flashcard 682: Which carbapenem has a decreased risk of seizure?_____

Answer: Meropenem

Flashcard 683: Treatment for Streptococcus agalactiae (GBS) is _____

Answer: penicillin G (specific)

Flashcard 684: Most Carbapenems are very useful against Pseudomonas aeruginosa, except _____ which has limited coverage

Answer: Ertapenem

Flashcard 685: Which enzyme in the bacterial folate synthesis pathway is inhibited by **Trimethoprim**?

Answer: Dihydrofolate reductase (DHFR)

Extra: Trimethoprim inhibits bacterial dihydrofolate reductase, which prevents the reduction of dihydrofolic acid to tetrahydrofolic acid (THF). Sulfonamides inhibit dihydropteroate synthase, the step immediately preceding this in the folate synthesis pathway.

Flashcard 686: What cutaneous pathology can be treated with tetracyclines?_____

Answer: Acne

Flashcard 687: Drug-induced _____ is an immunologic toxicity of Isoniazid use

Answer: lupus

Flashcard 688: What is the treatment for E. coli UTI?_____

Answer: TMP-SMX

Flashcard 689: What nephrotoxicity is caused by Sulfonamides?_____

Answer: Acute interstitial nephritis

Flashcard 690: Treatment for Staph aureus infections (not MRSA): _____

Answer: Nafcillin