Antibiotics — Flashcards

Flashcard 651: What is the susceptibility of Carbapenems to beta-lactamases?_____

Answer: Resistant

Flashcard 652: Rifampin is given with Dapsone because it _____ to Dapsone

Answer: delays resistance

Flashcard 653: Which specific process of bacterial protein synthesis is inhibited by **Macrolides**?

Answer: Translocation (50S ribosomal subunit inhibition)

Extra: Macrolides (e.g., Azithromycin, Erythromycin) bind to the 23S rRNA of the 50S subunit, blocking the translocation step where the peptidyl-tRNA moves from the A-site to the P-site.

Flashcard 654: Which Topoisomerases do Fluoroquinolones inhibit?_____

Answer: II and IV

Flashcard 655: What is the treatment of Leptospirosis?_____

Answer: Penicillin G

Flashcard 656: _____ macrolides must be given to treat trachoma (Chlamydia trachomatis serotype A, B, C)

Answer: Oral

Flashcard 657: Which protein synthesis inhibitor can cause dose-independent aplastic anemia?_____

Answer: Chloramphenicol

Flashcard 658: Pyrazinamide is associated with hyper-_____

Answer: uricemia

Flashcard 659: Which carbapenem is stable to dehydropeptidase I?_____

Answer: Meropenem

Flashcard 660: Which antibiotic is used as treatment for Bartonella henselae (cat-scratch)?_____

Answer: Azithromycin